bnl (Drosophila melanogaster)
ABF1

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF04684 (BAF1_ABF1) IPR006774 FBgn0014135 T000021_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables chemoattractant activity; fibroblast growth factor receptor binding activity; and morphogen activity. Involved in several processes, including negative regulation of hemocyte differentiation; open tracheal system development; and plasma membrane bounded cell projection assembly. Located in extracellular region. Colocalizes with cytoneme. Is expressed in several structures, including embryonic/larval nervous system; epithelial furrow; extended germ band embryo; larval imaginal tissue; and tracheal system. Human ortholog(s) of this gene implicated in several diseases, including LADD syndrome; artery disease (multiple); brain disease (multiple); cognitive disorder (multiple); and dysostosis (multiple). Orthologous to several human genes including FGF11 (fibroblast growth factor 11); FGF13 (fibroblast growth factor 13); and FGF4 (fibroblast growth factor 4). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
bnl
M01091_2.00		 Drosophila melanogaster
NRMATWYYNN
NNRRWATKYN		 PBM
Lambert et al.(2019)
pTH9833		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.700 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M01091_2.00 ABF1 57 152

DNA Binding Domains

Protein ID Domain From To Sequence
FBpp0310902 ABF1 152 247

Links

Other ABF1 family TFs
Other Drosophila melanogaster TFs

0 Related TFs

">No related TF found