CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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DREB2A
(
Arabidopsis thaliana
)
AP2
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00847 (AP2)
IPR001471
AT5G05410
T000504_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Encodes a transcription factor that specifically binds to DRE/CRT cis elements (responsive to drought and low-temperature stress). Belongs to the DREB subfamily A-2 of ERF/AP2 transcription factor family (DREB2A). There are eight members in this subfamily including DREB2B. The protein contains one AP2 domain. Overexpression of transcriptional activation domain of DREB2A resulted in significant drought stress tolerance but only slight freezing tolerance in transgenic Arabidopsis plants. Microarray and RNA gel blot analyses revealed that DREB2A regulates expression of many water stress#Aeiinducible genes.
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
DREB2A
M06655_2.00
Arabidopsis thaliana
NNNNHDHMACCGMCWYHNNNN
NNNNDRWGKCGGTKDHDNNNN
Dap-seq
OMalley et al.(2016)
DREB2_col_a
(Direct)
(Direct)
DREB2A
M06656_2.00
Arabidopsis thaliana
NHNHMACCGMCWTWD
HWAWGKCGGTKDNDN
Dap-seq
OMalley et al.(2016)
DREB2_colamp_a
(Direct)
(Direct)
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
PK07402.1
M01097_2.00
Cannabis sativa
NVRCCGMCH
DGKCGGYBN
PBM
Lambert et al.(2019)
pTH11436
0.687
0.857
For this family, TFs with SR scores >
0.677
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
AT5G05410.1
AP2
77
128
CSFRGVRQRIWGKWVAEIREPNRGSRLWLGTFPTAQEAASAYDEAAKAMYGP
AT5G05410.2
AP2
77
128
CSFRGVRQRIWGKWVAEIREPNRGSRLWLGTFPTAQEAASAYDEAAKAMYGP
Links
Other
AP2
family TFs
Other
Arabidopsis thaliana
TFs
44 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy