TF Information

Tfap2e *(Rattus norvegicus)* AP-2
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF03299 (TF_AP-2)	IPR013854	ENSRNOG00000027595	T010993_2.00	Ensembl (2018-Dec-8)	Link out
NCBI Gene Info: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Predicted to be involved in anatomical structure development; regulation of cell population proliferation; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human TFAP2E (transcription factor AP-2 epsilon). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
TFAP2E M04050_2.00	Homo sapiens	HSCCYSRGGSD	HSCCYSRGGSD	SELEX Yin et al.(2017) TFAP2E_FL_HT-SELEX_1	0.995	0.995
TFAP2E M04051_2.00	Homo sapiens	NSCCBBVGGSCA	TGSCCBVVGGSN	SELEX Yin et al.(2017) TFAP2E_FL_HT-SELEX_2	0.995	0.995
TFAP2E M04052_2.00	Homo sapiens	HSCCYSRGGSD	HSCCYSRGGSD	SELEX Yin et al.(2017) TFAP2E_FL_Methyl-HT-SELEX_1	0.995	0.995
TFAP2E M04053_2.00	Homo sapiens	NSCCYNRGGGCR	YGCCCYNRGGSN	SELEX Yin et al.(2017) TFAP2E_FL_Methyl-HT-SELEX_2	0.995	0.995
Tfap2e M00114_2.00	Mus musculus	NNGCCYBVGG	CCBVRGGCNN	PBM Badis et al.(2009) Tcfap2e_3713	0.990	0.990
Tfap2b M00112_2.00	Mus musculus	CCBSRGGSNW	WNSCCYSVGG	PBM Badis et al.(2009) Tcfap2b_3988	0.887	0.887
TFAP2B M02753_2.00	Homo sapiens	HSCCYBVRGGCD	HGCCYBVRGGSD	SELEX Jolma et al.(2013) TFAP2B_1	0.887	0.887
TFAP2B M02754_2.00	Homo sapiens	HGCCTSRGGCD	HGCCYSAGGCD	SELEX Jolma et al.(2013) TFAP2B_2	0.887	0.887
TFAP2B M02755_2.00	Homo sapiens	WGCCCYBVRGGCD	HGCCYBVRGGGCW	SELEX Jolma et al.(2013) TFAP2B_3	0.887	0.887
TFAP2B M04046_2.00	Homo sapiens	NSCCBNVGGSN	NSCCBNVGGSN	SELEX Yin et al.(2017) TFAP2B_eDBD_HT-SELEX	0.887	0.887
TFAP2B M08701_2.00	Homo sapiens	GSCYGVGGRV	BYCCBCRGSC	Misc Kulakovskiy et al.(2013) AP2B_HUMAN.H11MO.0.B	0.887	0.887
Tfap2b M08705_2.00	Mus musculus	GSCYGVGGRV	BYCCBCRGSC	Misc Kulakovskiy et al.(2013) AP2B_MOUSE.H11MO.0.B	0.887	0.887
TFAP2B M09750_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$AP2BETA_Q3	0.887	0.887
TFAP2B M04047_2.00	Homo sapiens	NSCCYNRGGSD	HSCCYNRGGSN	SELEX Yin et al.(2017) TFAP2B_eDBD_Methyl-HT-SELEX	0.887	0.887
Tfap2a M00111_2.00	Mus musculus	HSCCBNVRGS	SCYBNVGGSD	PBM Badis et al.(2009) Tcfap2a_2337	0.862	0.862
TFAP2A M02762_2.00	Homo sapiens	HGCCYBVRGGSD	HSCCYBVRGGCD	SELEX Jolma et al.(2013) TFAP2A_1	0.862	0.862
TFAP2A M02763_2.00	Homo sapiens	HGCCYSMGGCN	NGCCKSRGGCD	SELEX Jolma et al.(2013) TFAP2A_2	0.862	0.862
TFAP2A M02764_2.00	Homo sapiens	NSCCCBNVRGGSN	NSCCYBNVGGGSN	SELEX Jolma et al.(2013) TFAP2A_3	0.862	0.862
TFAP2A M02765_2.00	Homo sapiens	HGCCTSRGGCD	HGCCYSAGGCD	SELEX Jolma et al.(2013) TFAP2A_4	0.862	0.862
TFAP2A M02766_2.00	Homo sapiens	HGCCYBVRGGCD	HGCCYBVRGGCD	SELEX Jolma et al.(2013) TFAP2A_5	0.862	0.862
TFAP2A M02767_2.00	Homo sapiens	WGCCCYNVGGGCD	HGCCCBNRGGGCW	SELEX Jolma et al.(2013) TFAP2A_6	0.862	0.862
Tfap2a M02768_2.00	Mus musculus	HGCCYBVRGGCR	YGCCYBVRGGCD	SELEX Jolma et al.(2013) Tcfap2a_1	0.862	0.862
Tfap2a M02769_2.00	Mus musculus	HGCCTSRGGCD	HGCCYSAGGCD	SELEX Jolma et al.(2013) Tcfap2a_2	0.862	0.862
Tfap2a M02770_2.00	Mus musculus	WGCCCYBVGGGCD	HGCCCBVRGGGCW	SELEX Jolma et al.(2013) Tcfap2a_3	0.862	0.862
TFAP2A M04054_2.00	Homo sapiens	NGCCBSVGGCN	NGCCBSVGGCN	SELEX Yin et al.(2017) TFAP2A_FL_HT-SELEX	0.862	0.862
TFAP2A M07784_2.00	Homo sapiens	NBNSCCYSRGGSCWN	NWGSCCYSRGGSNVN	ChIP-seq Gerstein et al.(2012) HeLa-S3_AP2ALPHA_UCD	0.862	0.862
TFAP2A M08703_2.00	Homo sapiens	NHDSCCYCAGGSHWN	NWDSCCTGRGGSHDN	Misc Kulakovskiy et al.(2013) AP2A_HUMAN.H11MO.0.A	0.862	0.862
Tfap2a M08704_2.00	Mus musculus	SCCYCRGGSNNN	NNNSCCYGRGGS	Misc Kulakovskiy et al.(2013) AP2A_MOUSE.H11MO.0.A	0.862	0.862
TFAP2A M09755_2.00	Homo sapiens	GCCBBVVGS	SCBBVVGGC	Transfac Matys et al.(2006) V$AP2ALPHA_01	0.862	0.862
TFAP2A M09756_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$AP2ALPHA_02	0.862	0.862
TFAP2A M09757_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$AP2ALPHA_03	0.862	0.862
TFAP2A M09758_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$AP2ALPHA_Q4	0.862	0.862
TFAP2A M09759_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$AP2ALPHA_Q6	0.862	0.862
TFAP2A M09760_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$TFAP2A_09	0.862	0.862
TFAP2A M04055_2.00	Homo sapiens	NSCCTNAGGSN	NSCCTNAGGSN	SELEX Yin et al.(2017) TFAP2A_FL_Methyl-HT-SELEX	0.862	0.862
Tfap2c M00113_2.00	Mus musculus	NSCCBBVGGS	SCCBVVGGSN	PBM Badis et al.(2009) Tcfap2c_2912	0.779	0.779
Tfap2c M08706_2.00	Mus musculus	NNSCCYGRGGSNN	NNSCCYCRGGSNN	Misc Kulakovskiy et al.(2013) AP2C_MOUSE.H11MO.0.A	0.779	0.779
TFAP2C M02756_2.00	Homo sapiens	HSCCYBVRGGCD	HGCCYBVRGGSD	SELEX Jolma et al.(2013) TFAP2C_1	0.754	0.754
TFAP2C M02757_2.00	Homo sapiens	HGCCTBRGGCD	HGCCYVAGGCD	SELEX Jolma et al.(2013) TFAP2C_2	0.754	0.754
TFAP2C M02758_2.00	Homo sapiens	WGCCCYNRGGGCD	HGCCCYNRGGGCW	SELEX Jolma et al.(2013) TFAP2C_3	0.754	0.754
TFAP2C M02759_2.00	Homo sapiens	HSCCYBVRGGCD	HGCCYBVRGGSD	SELEX Jolma et al.(2013) TFAP2C_4	0.754	0.754
TFAP2C M02760_2.00	Homo sapiens	NGCCCBNVRGGCN	NGCCYBNVGGGCN	SELEX Jolma et al.(2013) TFAP2C_5	0.754	0.754
TFAP2C M02761_2.00	Homo sapiens	HGCCTBRGGCD	HGCCYVAGGCD	SELEX Jolma et al.(2013) TFAP2C_6	0.754	0.754
TFAP2C M04048_2.00	Homo sapiens	NSCYHNHRGBN	NVCYDNDRGSN	SELEX Yin et al.(2017) TFAP2C_eDBD_HT-SELEX	0.754	0.754
TFAP2C M07783_2.00	Homo sapiens	NSCCYSRGGSCANDN	NHNTGSCCYSRGGSN	ChIP-seq Gerstein et al.(2012) HeLa-S3_AP2GAMMA_UCD	0.754	0.754
TFAP2C M08702_2.00	Homo sapiens	NDSCCYCAGGSHHN	NDDSCCTGRGGSHN	Misc Kulakovskiy et al.(2013) AP2C_HUMAN.H11MO.0.A	0.754	0.754
TFAP2C M09451_2.00	Homo sapiens	SCCYSRGGSHNN	NNDSCCYSRGGS	Misc Heinz et al.(2010) MCF7-TFAP2C_GSE21234	0.754	0.754
TFAP2C M09751_2.00	Homo sapiens	GCCBBVRGS	SCYBVVGGC	Transfac Matys et al.(2006) V$AP2GAMMA_01	0.754	0.754
TFAP2C M09752_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$AP2GAMMA_Q4	0.754	0.754
TFAP2C M09753_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$AP2GAMMA_Q5_01	0.754	0.754
TFAP2C M09754_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$AP2GAMMA_Q5	0.754	0.754
TFAP2C M04049_2.00	Homo sapiens	NSCCYNRGGSN	NSCCYNRGGSN	SELEX Yin et al.(2017) TFAP2C_eDBD_Methyl-HT-SELEX	0.754	0.754
AP-2 M03584_2.00	Drosophila melanogaster	HGCCYSRGGCD	HGCCYSRGGCD	SELEX Nitta et al.(2015) AP-2_1	0.708	0.708
AP-2 M03585_2.00	Drosophila melanogaster	HGCCYBVRGGCD	HGCCYBVRGGCD	SELEX Nitta et al.(2015) AP-2_2	0.708	0.708
AP-2 M03586_2.00	Drosophila melanogaster	NSCCYBNVRGGCN	NGCCYBNVRGGSN	SELEX Nitta et al.(2015) AP-2_3	0.708	0.708
AP-2 M03587_2.00	Drosophila melanogaster	HGCCYNRGGCD	HGCCYNRGGCD	SELEX Nitta et al.(2015) AP-2_4	0.708	0.708
AP-2 M03588_2.00	Drosophila melanogaster	HSCCYBVRGGSD	HSCCYBVRGGSD	SELEX Nitta et al.(2015) AP-2_5	0.708	0.708
AP-2 M03589_2.00	Drosophila melanogaster	HGCCYBNVRGGCD	HGCCYBNVRGGCD	SELEX Nitta et al.(2015) AP-2_6	0.708	0.708
For this family, TFs with SR scores > 0.700* will likely have a similar motif*

DNA Binding Domains

Protein ID	Domain	From	To	Sequence
ENSRNOP00000032823	AP-2	216	416	EVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRCLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAAAEYLGRQHADPGELHSRKSMLLAAKQICKEFADLMAQDRSPLGNSRPALILEPGVQSCLTHFSLITHGFGGPAICAALTAFQNYLLESLKGL

Links
Other AP-2 family TFs
Other *Rattus norvegicus* TFs

Invalid Input OrderBy

376 Related TFs

Name	Species	Gene ID	Motif Evidence	SR Score	Action

Tfap2e (Rattus norvegicus) AP-2

TF Information

Directly determined binding motifs

Motifs from related TFs

DNA Binding Domains

Links

376 Related TFs

Invalid Input OrderBy

Tfap2e **(Rattus norvegicus)
AP-2**