Arid5a (Mus musculus)
ARID/BRIGHT

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF01388 (ARID) IPR001606 ENSMUSG00000037447 T014644_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables RNA stem-loop binding activity and chromatin binding activity. Involved in cellular response to lipopolysaccharide; positive regulation of T-helper 17 type immune response; and positive regulation of cytokine production. Acts upstream of or within chondrocyte differentiation; positive regulation of histone acetylation; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including ear; heart; hemolymphoid system; nervous system; and neural retina. Orthologous to human ARID5A (AT-rich interaction domain 5A). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Arid5a
M00116_2.00		 Mus musculus
NHAATATTDNN
NNHAATATTDN		 PBM
Badis et al.(2009)
Arid5a_3770		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Arid5a
M01663_2.00 		Rattus norvegicus
NNNRWATHNN
NNDATWYNNN		 PBM
Weirauch et al.(2014)
pTH5121 		0.785 1.000
arid6
M01657_2.00 		Danio rerio
NNRWATYN
NRATWYNN		 PBM
Weirauch et al.(2014)
pTH5120 		0.649 0.647
Arid5b
M01661_2.00 		Mus musculus
NDATWHNN
NNDWATHN		 PBM
Weirauch et al.(2014)
pTH4426 		0.632 0.753
ARID5B
M08707_2.00 		Homo sapiens
DNBKDRTATTSKD
HMSAATAYHMVNH		 Misc
Kulakovskiy et al.(2013)
ARI5B_HUMAN.H11MO.0.C 		0.632 0.753
Arid5b
M08708_2.00 		Mus musculus
DNBKDRTATTSKD
HMSAATAYHMVNH		 Misc
Kulakovskiy et al.(2013)
ARI5B_MOUSE.H11MO.0.C 		0.632 0.753
ARID5B
M09767_2.00 		Homo sapiens
KBDGTATTGTRSWB
VWSYACAATACHVM		 Transfac
Matys et al.(2006)
V$MRF2_01 		0.632 0.753
e_gw.4.260.1_CONSTRUCT
M01668_2.00 		PBM CONSTRUCTS
NNNDATHNNN
NNNDATHNNN		 PBM
Weirauch et al.(2014)
pTH5122 		0.493 0.588
For this family, TFs with SR scores > 0.422 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00116_2.00 ARID/BRIGHT 21 106

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000095385 ARID/BRIGHT 81 166
ENSMUSP00000110683 ARID/BRIGHT 51 89
ENSMUSP00000110683 ARID/BRIGHT 164 231
ENSMUSP00000110684 ARID/BRIGHT 52 137
ENSMUSP00000115490 ARID/BRIGHT 51 136

Links

Other ARID/BRIGHT family TFs
Other Mus musculus TFs

Invalid Input OrderBy

155 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action