| NCBI Gene Info:Enables DNA-binding transcription factor binding activity; chromatin binding activity; and transcription coregulator binding activity. Involved in negative regulation of neuron death; positive regulation of Notch signaling pathway; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Part of Sin3-type complex. Is expressed in several structures, including anterior endoderm anlage; central nervous system; embryonic/larval midgut; germ layer; and ovariole. Orthologous to human ARID4A (AT-rich interaction domain 4A) and ARID4B (AT-rich interaction domain 4B). [provided by Alliance of Genome Resources, Apr 2022] |