| NCBI Gene Info:Enables DNA binding activity. Involved in several processes, including generation of neurons; imaginal disc development; and regulation of transcription, DNA-templated. Located in nucleus and polytene chromosome. Part of brahma complex. Is expressed in several structures, including adult brain cell body rind; embryonic/larval fat body; embryonic/larval salivary gland; and imaginal disc. Human ortholog(s) of this gene implicated in several diseases, including Coffin-Siris syndrome (multiple); breast cancer; carcinoma (multiple); gastrointestinal system cancer (multiple); and neuroblastoma. Orthologous to human ARID1A (AT-rich interaction domain 1A) and ARID1B (AT-rich interaction domain 1B). [provided by Alliance of Genome Resources, Apr 2022] |