ECM5 (Saccharomyces cerevisiae)
ARID/BRIGHT

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF01388 (ARID) IPR001606 YMR176W T015814_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable histone H3-tri/di/monomethyl-lysine-4 demethylase activity. Involved in cellular response to oxidative stress. Located in cytoplasm and nucleus. Part of Snt2C complex. Human ortholog(s) of this gene implicated in ankylosing spondylitis; autosomal recessive non-syndromic intellectual disability; breast cancer; high grade glioma; and syndromic X-linked intellectual disability Claes-Jensen type. Orthologous to several human genes including KDM5A (lysine demethylase 5A); KDM5B (lysine demethylase 5B); and KDM5C (lysine demethylase 5C). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
NCU01238
M01669_2.00 		Neurospora crassa
NYATNNNN
NNNNATRN		 PBM
Weirauch et al.(2014)
pTH8942 		0.514 0.506
For this family, TFs with SR scores > 0.422 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
YMR176W ARID/BRIGHT 187 275

Links

Other ARID/BRIGHT family TFs
Other Saccharomyces cerevisiae TFs

Invalid Input OrderBy

185 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action