ENSBTAP00000008847-D1 (Bos grunniens)
ARID/BRIGHT

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF01388 (ARID) IPR001606 ENSBTAP00000008847-D1 T015892_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Arid5b
M01661_2.00
Mus musculus
NDATWHNN

NNDWATHN
PBM
Weirauch et al.(2014)
pTH4426
0.785 1.000
ARID5B
M08707_2.00
Homo sapiens
DNBKDRTATTSKD

HMSAATAYHMVNH
Misc
Kulakovskiy et al.(2013)
ARI5B_HUMAN.H11MO.0.C
0.785 1.000
Arid5b
M08708_2.00
Mus musculus
DNBKDRTATTSKD

HMSAATAYHMVNH
Misc
Kulakovskiy et al.(2013)
ARI5B_MOUSE.H11MO.0.C
0.785 1.000
ARID5B
M09767_2.00
Homo sapiens
KBDGTATTGTRSWB

VWSYACAATACHVM
Transfac
Matys et al.(2006)
V$MRF2_01
0.785 1.000
Arid5a
M00116_2.00
Mus musculus
NHAATATTDNN

NNHAATATTDN
PBM
Badis et al.(2009)
Arid5a_3770
0.632 0.744
Arid5a
M01663_2.00
Rattus norvegicus
NNNRWATHNN

NNDATWYNNN
PBM
Weirauch et al.(2014)
pTH5121
0.632 0.744
arid6
M01657_2.00
Danio rerio
NNRWATYN

NRATWYNN
PBM
Weirauch et al.(2014)
pTH5120
0.605 0.605
e_gw.4.260.1_CONSTRUCT
M01668_2.00
PBM CONSTRUCTS
NNNDATHNNN

NNNDATHNNN
PBM
Weirauch et al.(2014)
pTH5122
0.482 0.593
For this family, TFs with SR scores > 0.422 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSBTAP00000008847-D1 ARID/BRIGHT 319 405

Links

Other ARID/BRIGHT family TFs
Other Bos grunniens TFs

149 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ARID5B Ornithorhynchus anatinus ENSOANG00000015260 I 0.785
ENSNLEG00000012110 Nomascus leucogenys ENSNLEG00000012110 I 0.785
Arid5b Mus musculus ENSMUSG00000019947 D 0.785
ENSOARG00000004403 Ovis aries ENSOARG00000004403 I 0.785
ARID5B Oryctolagus cuniculus ENSOCUG00000027029 I 0.785
ENSPSIG00000010908 Pelodiscus sinensis ENSPSIG00000010908 I 0.785
ARID5B Procavia capensis ENSPCAG00000002044 I 0.785
ENSPANG00000022067 Papio anubis ENSPANG00000022067 I 0.785
ENSMPUG00000011076 Mustela putorius furo ENSMPUG00000011076 I 0.785
ARID5B Monodelphis domestica ENSMODG00000017102 I 0.785
ARID5B Loxodonta africana ENSLAFG00000015576 I 0.785
ENSLACG00000015032 Latimeria chalumnae ENSLACG00000015032 I 0.785
ARID5B Gorilla gorilla ENSGGOG00000004127 I 0.785
ARID5B Meleagris gallopavo ENSMGAG00000003626 I 0.785
ENSMICG00000010866 Microcebus murinus ENSMICG00000010866 I 0.785
ARID5B Macaca mulatta ENSMMUG00000000424 I 0.785
ARID5B Myotis lucifugus ENSMLUG00000013447 I 0.785
ARID5B Pan troglodytes ENSPTRG00000002534 I 0.785
ARID5B Pteropus vampyrus ENSPVAG00000010482 I 0.785
Gfo_R015732 Geospiza fortis Gfo_R015732 I 0.785
ENSP00000279873 Macaca fascicularis ENSP00000279873 I 0.785
Cmyd_10021475 Chelonia mydas Cmyd_10021475 I 0.785
Myotis_brandtii_ARID5B_10031403 Myotis brandtii Myotis_brandtii_ARID5B_10031403 I 0.785
Ogr08677 Ophisaurus gracilis Ogr08677 I 0.785
arid5b Xenopus tropicalis XB-GENE-1007579 I 0.785
Tal_R007047 Tyto alba Tal_R007047 I 0.785
Pvit_18395 Pogona vitticeps Pvit_18395 I 0.785
Brh_R002693 Buceros rhinoceros Brh_R002693 I 0.785
Alligator_sinensis_CCG017455.1 Alligator sinensis Alligator_sinensis_CCG017455.1 I 0.785
ARID5B Sus scrofa ENSSSCG00000010219 I 0.785
ENSSHAG00000012252 Sarcophilus harrisii ENSSHAG00000012252 I 0.785
ARID5B Sorex araneus ENSSARG00000002423 I 0.785
ARID5B Taeniopygia guttata ENSTGUG00000005270 I 0.785
ENSTSYG00000010758 Tarsius syrichta ENSTSYG00000010758 I 0.785
Afo_R009473 Aptenodytes forsteri Afo_R009473 I 0.785
Aan_R006833 Calypte anna Aan_R006833 I 0.785
ENSGALG00000002991 Gallus gallus ENSGALG00000002991 I 0.785
ARID5B Otolemur garnettii ENSOGAG00000015939 I 0.785
ENSCSAG00000007410 Chlorocebus sabaeus ENSCSAG00000007410 I 0.785
ENSCPOG00000003685 Cavia porcellus ENSCPOG00000003685 I 0.785
ARID5B Callithrix jacchus ENSCJAG00000007072 I 0.785
ARID5B Dasypus novemcinctus ENSDNOG00000043861 I 0.785
ARID5B Equus caballus ENSECAG00000019795 I 0.785
ARID5B Echinops telfairi ENSETEG00000002612 I 0.785
ARID5B Erinaceus europaeus ENSEEUG00000000691 I 0.785
ARID5B Felis catus ENSFCAG00000026767 I 0.785
ARID5B Choloepus hoffmanni ENSCHOG00000011695 I 0.785
ARID5B Homo sapiens ENSG00000150347 D 0.785
ARID5B Anolis carolinensis ENSACAG00000010922 I 0.785
ENSFALG00000013304 Ficedula albicollis ENSFALG00000013304 I 0.785
ENSAPLG00000010915 Anas platyrhynchos ENSAPLG00000010915 I 0.785
ARID5B Canis familiaris ENSCAFG00000012991 I 0.785
ARID5B Bos taurus ENSBTAG00000006729 I 0.785
ENSAMEG00000003626 Ailuropoda melanoleuca ENSAMEG00000003626 I 0.785
ENSPPYG00000002417 Pongo abelii ENSPPYG00000002417 I 0.767
ENSAMXG00000012004 Astyanax mexicanus ENSAMXG00000012004 I 0.760
arid5b Danio rerio ENSDARG00000037196 I 0.760
ENSLOCG00000006809 Lepisosteus oculatus ENSLOCG00000006809 I 0.760
ENSMEUG00000005354 Macropus eugenii ENSMEUG00000005354 I 0.743
arid5b Takifugu rubripes ENSTRUG00000010671 I 0.738
ENSONIG00000000889 Oreochromis niloticus ENSONIG00000000889 I 0.738
ENSPFOG00000012334 Poecilia formosa ENSPFOG00000012334 I 0.738
arid5b Gasterosteus aculeatus ENSGACG00000010603 I 0.738
ENSXMAG00000018209 Xiphophorus maculatus ENSXMAG00000018209 I 0.738
ENSORLG00000004756 Oryzias latipes ENSORLG00000004756 I 0.738
arid5b Tetraodon nigroviridis ENSTNIG00000007478 I 0.738
ENSGMOG00000004984 Gadus morhua ENSGMOG00000004984 I 0.738
arid5a Danio rerio ENSDARG00000077120 I 0.660
ENSPMAG00000002699 Petromyzon marinus ENSPMAG00000002699 I 0.658
ENSLACG00000014124 Latimeria chalumnae ENSLACG00000014124 I 0.648
ENSGACG00000015846 Gasterosteus aculeatus ENSGACG00000015846 I 0.646
Alligator_sinensis_CCG013281.1 Alligator sinensis Alligator_sinensis_CCG013281.1 I 0.646
ARID5A Pteropus vampyrus ENSPVAG00000009400 I 0.632
Arid5a Rattus norvegicus ENSRNOG00000015382 D 0.632
ARID5A Cavia porcellus ENSCPOG00000026444 I 0.632
ARID5A Pan troglodytes ENSPTRG00000012234 I 0.632
ARID5A Felis catus ENSFCAG00000024950 I 0.632
ARID5A Homo sapiens ENSG00000196843 I 0.632
ENSPSIG00000014127 Pelodiscus sinensis ENSPSIG00000014127 I 0.632
ENSCSAG00000017355 Chlorocebus sabaeus ENSCSAG00000017355 I 0.632
ENSAMEG00000008932 Ailuropoda melanoleuca ENSAMEG00000008932 I 0.632
Myotis_brandtii_ARID5A_10013684 Myotis brandtii Myotis_brandtii_ARID5A_10013684 I 0.632
ENSPPYG00000012072 Pongo abelii ENSPPYG00000012072 I 0.632
ARID5A Tursiops truncatus ENSTTRG00000007812 I 0.632
Cmyd_10001620 Chelonia mydas Cmyd_10001620 I 0.632
ARID5A Canis familiaris ENSCAFG00000006546 I 0.632
ARID5A Gorilla gorilla ENSGGOG00000017068 I 0.632
ARID5A Loxodonta africana ENSLAFG00000009162 I 0.632
ARID5A Callithrix jacchus ENSCJAG00000007759 I 0.632
ARID5A Bos taurus ENSBTAG00000014090 I 0.632
ENSSTOG00000019546 Ictidomys tridecemlineatus ENSSTOG00000019546 I 0.632
ARID5A Sus scrofa ENSSSCG00000008123 I 0.632
ENSSHAG00000018209 Sarcophilus harrisii ENSSHAG00000018209 I 0.632
ARID5A Erinaceus europaeus ENSEEUG00000008247 I 0.632
ENSMEUG00000014406 Macropus eugenii ENSMEUG00000014406 I 0.632
ENSMPUG00000008907 Mustela putorius furo ENSMPUG00000008907 I 0.632
ARID5A Dasypus novemcinctus ENSDNOG00000035690 I 0.632
Arid5a Dipodomys ordii ENSDORG00000002540 I 0.632
ARID5A Equus caballus ENSECAG00000023667 I 0.632
ARID5A Monodelphis domestica ENSMODG00000008611 I 0.632
Arid5a Mus musculus ENSMUSG00000037447 D 0.632
ARID5A Myotis lucifugus ENSMLUG00000003208 I 0.632
ARID5A Otolemur garnettii ENSOGAG00000004116 I 0.632
ENSPANG00000012565 Papio anubis ENSPANG00000012565 I 0.632
ARID5A Procavia capensis ENSPCAG00000006363 I 0.632
ENSAMXG00000005409 Astyanax mexicanus ENSAMXG00000005409 I 0.627
ENSLOCG00000015055 Lepisosteus oculatus ENSLOCG00000015055 I 0.627
Ogr03010 Ophisaurus gracilis Ogr03010 I 0.619
ENSORLG00000018351 Oryzias latipes ENSORLG00000018351 I 0.616
ENSTRUG00000001547 Takifugu rubripes ENSTRUG00000001547 I 0.616
ENSXMAG00000011937 Xiphophorus maculatus ENSXMAG00000011937 I 0.613
ENSPFOG00000022560 Poecilia formosa ENSPFOG00000022560 I 0.613
arid6 Danio rerio ENSDARG00000069988 D 0.605
ENSLOCG00000005151 Lepisosteus oculatus ENSLOCG00000005151 I 0.605
ENSTNIG00000013457 Tetraodon nigroviridis ENSTNIG00000013457 I 0.599
ARID5A Ochotona princeps ENSOPRG00000015571 I 0.593
ENSGMOG00000008075 Gadus morhua ENSGMOG00000008075 I 0.592
ENSPFOG00000012795 Poecilia formosa ENSPFOG00000012795 I 0.590
ENSONIG00000010644 Oreochromis niloticus ENSONIG00000010644 I 0.590
ENSORLG00000011620 Oryzias latipes ENSORLG00000011620 I 0.590
ENSTNIG00000006278 Tetraodon nigroviridis ENSTNIG00000006278 I 0.590
ENSXMAG00000001883 Xiphophorus maculatus ENSXMAG00000001883 I 0.590
ENSPMAG00000009067 Petromyzon marinus ENSPMAG00000009067 I 0.586
ENSGALG00000027335 Gallus gallus ENSGALG00000027335 I 0.583
ENSFALG00000000299 Ficedula albicollis ENSFALG00000000299 I 0.583
ENSTGUG00000015609 Taeniopygia guttata ENSTGUG00000015609 I 0.583
zgc:77151 Danio rerio ENSDARG00000054307 I 0.578
ENSPFOG00000010024 Poecilia formosa ENSPFOG00000010024 I 0.578
ENSAMXG00000006897 Astyanax mexicanus ENSAMXG00000006897 I 0.578
NV18117 Nasonia vitripennis NV18117 I 0.568
ENSSTOG00000023423 Ictidomys tridecemlineatus ENSSTOG00000023423 I 0.559
ARID5A Macaca mulatta ENSMMUG00000030744 I 0.558
SMAR000821 Strigamia maritima SMAR000821 I 0.554
L798_01524 Zootermopsis nevadensis L798_01524 I 0.552
ISCW010123 Ixodes scapularis ISCW010123 I 0.550
Ocbimv22018673m.g Octopus bimaculoides Ocbimv22018673m.g I 0.544
Sakowv30045810m.g Saccoglossus kowalevskii Sakowv30045810m.g I 0.543
SPU_011640 Strongylocentrotus purpuratus SPU_011640 I 0.538
Cflo_07446--XP_395512.3_APIME Camponotus floridanus Cflo_07446--XP_395512.3_APIME I 0.530
GB52601 Apis mellifera GB52601 I 0.530
Hsal_01506--XP_395512.3_APIME Harpegnathos saltator Hsal_01506--XP_395512.3_APIME I 0.530
CapteG220448 Capitella teleta CapteG220448 I 0.501
ENSCING00000013307 Ciona intestinalis ENSCING00000013307 I 0.494
NEMVEDRAFT_v1g81183 Nematostella vectensis NEMVEDRAFT_v1g81183 I 0.482
e_gw.4.260.1_CONSTRUCT PBM CONSTRUCTS e_gw.4.260.1_CONSTRUCT D 0.482
fgenesh2_pg.scaffold_164000022 Branchiostoma floridae fgenesh2_pg.scaffold_164000022 I 0.455
tetur19g00310 Tetranychus urticae tetur19g00310 I 0.443
ENSLOCG00000012316 Lepisosteus oculatus ENSLOCG00000012316 I 0.431
ARID5A Oryctolagus cuniculus ENSOCUG00000012101 I 0.428