CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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Arid2
(
Mus musculus
)
ARID/BRIGHT,RFX
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF01388 (ARID)
PF02257 (RFX_DNA_binding)
IPR001606
IPR003150
ENSMUSG00000033237
T016880_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Predicted to enable DNA binding activity and metal ion binding activity. Acts upstream of or within embryonic organ development; heart development; and homeostatic process. Predicted to be located in nucleoplasm and plasma membrane. Predicted to be part of transcription regulator complex. Is expressed in early conceptus and genitourinary system. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 6; colorectal cancer; and hepatocellular carcinoma. Orthologous to human ARID2 (AT-rich interaction domain 2). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
No direct experiments
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
TTHERM_00243900
M01666_2.00
Tetrahymena thermophila
NDDATYANN
NNTRATHHN
PBM
Weirauch et al.(2014)
pTH5128
0.459
0.419
GSPATT00004674001
M01665_2.00
Paramecium tetraurelia
NNATYHNN
NNDRATNN
PBM
Weirauch et al.(2014)
pTH5124
0.459
0.407
For this family, TFs with SR scores >
0.700
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSMUSP00000093969
ARID/BRIGHT
15
101
KGLAFLDELRQFHHSRGSPFKKIPAVGGKELDLHGLYTRVTTLGGFAKVSEKNQWGEIVEEFNFPRSCSNAAFALKQYYLRYLEKYE
ENSMUSP00000093969
RFX
521
603
EKFACQWLNAHFEVNPDCSVSRAEMYSEYLSTCSKLARGGILTSTGFYKCLRTVFPNHTVKRVEDSTSSGQAHIHVIGVKRRA
ENSMUSP00000135829
ARID/BRIGHT
15
101
KGLAFLDELRQFHHSRGSPFKKIPAVGGKELDLHGLYTRVTTLGGFAKVSEKNQWGEIVEEFNFPRSCSNAAFALKQYYLRYLEKYE
Links
Other
ARID/BRIGHT,RFX
family TFs
Other
Mus musculus
TFs
54 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy