TF Information

BHLH13 *(Arabidopsis thaliana)* bHLH
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF00010 (HLH)	IPR001092	AT1G01260	T030575_2.00	Ensembl (2018-Dec-8)	Link out
NCBI Gene Info: JAZ1 is a nuclear-localized protein involved in jasmonate signaling. JAZ1 transcript levels rise in response to a jasmonate stimulus. JAZ1 can interact with the COI1 F-box subunit of an SCF E3 ubiquitin ligase in a yeast-two-hybrid assay only in the presence of jasmonate-isoleucine (JA-ILE) or coronatine. Application of jasmonate methyl ester to Arabidopsis roots reduces the levels of a JAZ1:GUS fusion protein, presumably by stimulating ubiquitin-proteasome-mediated degradation. The Jas domain appears to be important for JAZ1-COI1 interactions in the presence of coronatine. Two positive residues (R205 and R206) in the Jas domain shown to be important for coronatine -dependent COI1 binding are not required for binding AtMYC2.
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
BHLH13 M01698_2.00	Arabidopsis thaliana	MCACGTGV	BCACGTGK	PBM Weirauch et al.(2014) pTH7565	(Direct)	(Direct)
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
PK18474.1 M01127_2.00	Cannabis sativa	NRCACGTGCN	NGCACGTGYN	PBM Lambert et al.(2019) pTH10273	0.879	0.898
PK18474.1 M01768_2.00	Cannabis sativa	NCACGWK	MWCGTGN	PBM Weirauch et al.(2014) pTH9589	0.879	0.898
MYC2 M01699_2.00	Arabidopsis thaliana	NNCACGTGNN	NNCACGTGNN	PBM Weirauch et al.(2014) pTH8083	0.879	0.878
MYC3 M01712_2.00	Arabidopsis thaliana	MWYGTGNNNN	NNNNCACRWK	PBM Weirauch et al.(2014) pTH8854	0.879	0.878
MYC4 M01707_2.00	Arabidopsis thaliana	NNCACGTGNN	NNCACGTGNN	PBM Weirauch et al.(2014) pTH8260	0.879	0.857
OS01G0235700 M09894_2.00	Oryza sativa	Transfac license required	Transfac license required	Transfac Matys et al.(2006) P$BHLH66_01	0.879	0.857
AT2G22750 M06730_2.00	Arabidopsis thaliana	MRYGTKDNHCACGTGNN	NNCACGTGDNHMACRYK	Dap-seq OMalley et al.(2016) bHLH18_col_a	0.846	0.571
For this family, TFs with SR scores > 0.838* will likely have a similar motif*

Experimental Constructs

Motif ID	Domain	From	To	Sequence
M01698_2.00	bHLH	51	99	ALNHVEAERQRREKLNQRFYALRSVVPNISKMDKASLLGDAVSYINELH

DNA Binding Domains

Protein ID	Domain	From	To	Sequence
AT1G01260.1	bHLH	431	479	ALNHVEAERQRREKLNQRFYALRSVVPNISKMDKASLLGDAVSYINELH
AT1G01260.2	bHLH	431	479	ALNHVEAERQRREKLNQRFYALRSVVPNISKMDKASLLGDAVSYINELH
AT1G01260.3	bHLH	431	479	ALNHVEAERQRREKLNQRFYALRSVVPNISKMDKASLLGDAVSYINELH

Links
Other bHLH family TFs
Other *Arabidopsis thaliana* TFs

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467 Related TFs

Name	Species	Gene ID	Motif Evidence	SR Score	Action