ARNTL2 (Bos taurus)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSBTAG00000011804 T033075_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene encodes a basic helix-loop-helix transcription factor belonging to the PAS (PER, ARNT, SIM) superfamily. The PAS proteins play important roles in adaptation to low atmospheric and cellular oxygen levels, exposure to certain environmental pollutants, and diurnal oscillations in light and temperature. This protein forms a transcriptionally active heterodimer with the circadian CLOCK protein, the structurally related MOP4, and hypoxia-inducible factors, such as HIF1alpha. Consistent with its role as a biologically relevant partner of circadian and hypoxia factors, this protein is coexpressed in regions of the brain such as the thalamus, hypothalamus, and amygdala. [provided by RefSeq, Feb 2014]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
ENSBTAP00000040847 bHLH 99 151

Links

Other bHLH family TFs
Other Bos taurus TFs

28 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ENSP00000266503-D1 Bos grunniens ENSP00000266503-D1 N 0.914
ENSOARG00000019779 Ovis aries ENSOARG00000019779 N 0.893
ARNTL2 Tursiops truncatus ENSTTRG00000012339 N 0.850
ENSTSYG00000005541 Tarsius syrichta ENSTSYG00000005541 N 0.850
ARNTL2 Pan troglodytes ENSPTRG00000004788 N 0.850
ENSTGUG00000012163 Taeniopygia guttata ENSTGUG00000012163 N 0.850
Aan_R007949 Calypte anna Aan_R007949 N 0.850
Brh_R011091 Buceros rhinoceros Brh_R011091 N 0.850
Gfo_R015185 Geospiza fortis Gfo_R015185 N 0.850
Tal_R011603 Tyto alba Tal_R011603 N 0.850
ENSP00000266503 Macaca fascicularis ENSP00000266503 N 0.850
Cmyd_10013756 Chelonia mydas Cmyd_10013756 N 0.850
ENSPSIG00000009416 Pelodiscus sinensis ENSPSIG00000009416 N 0.850
Afo_R006305 Aptenodytes forsteri Afo_R006305 N 0.850
ENSPPYG00000004380 Pongo abelii ENSPPYG00000004380 N 0.850
ARNTL2 Homo sapiens ENSG00000029153 N 0.850
ARNTL2 Gallus gallus ENSGALG00000014096 N 0.850
ENSFALG00000003942 Ficedula albicollis ENSFALG00000003942 N 0.850
ENSCSAG00000007636 Chlorocebus sabaeus ENSCSAG00000007636 N 0.850
ENSAPLG00000008758 Anas platyrhynchos ENSAPLG00000008758 N 0.850
ARNTL2 Meleagris gallopavo ENSMGAG00000013735 N 0.850
ARNTL2 Macaca mulatta ENSMMUG00000023249 N 0.850
ARNTL2 Procavia capensis ENSPCAG00000008486 N 0.850
ENSPANG00000004474 Papio anubis ENSPANG00000004474 N 0.850
ENSNLEG00000005463 Nomascus leucogenys ENSNLEG00000005463 N 0.850
ENSAMEG00000011610 Ailuropoda melanoleuca ENSAMEG00000011610 N 0.850
ENSMPUG00000010512 Mustela putorius furo ENSMPUG00000010512 N 0.850
ARNTL2 Pteropus vampyrus ENSPVAG00000013771 N 0.848