TF Information

ptf1a *(Danio rerio)* bHLH
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF00010 (HLH)	IPR001092	ENSDARG00000014479	T033641_2.00	Ensembl (2018-Dec-8)	Link out
NCBI Gene Info: Enables DNA-binding transcription factor activity and sequence-specific DNA binding activity. Acts upstream of or within animal organ development and positive regulation of transcription, DNA-templated. Predicted to be located in cytoplasm and nucleus. Predicted to be part of transcription regulator complex. Is expressed in several structures, including exocrine cell; intestinal bulb primordium; mid intestine; nervous system; and pancreatic system. Human ortholog(s) of this gene implicated in pancreatic agenesis. Orthologous to human PTF1A (pancreas associated transcription factor 1a). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
PTF1A M04156_2.00	Homo sapiens	AACAGCTGACRB	VYGTCAGCTGTT	SELEX Yin et al.(2017) PTF1A_eDBD_HT-SELEX	0.890	0.981
PTF1A M08736_2.00	Homo sapiens	SCAGCTGBYNBNNYYYHN	NDRRRNNVNRVCAGCTGS	Misc Kulakovskiy et al.(2013) PTF1A_HUMAN.H11MO.0.B	0.890	0.981
Ptf1a M08757_2.00	Mus musculus	SCAGCTGBYNBNNYYYHN	NDRRRNNVNRVCAGCTGS	Misc Kulakovskiy et al.(2013) PTF1A_MOUSE.H11MO.0.A	0.890	0.981
Ptf1a M09470_2.00	Mus musculus	NVVCASSTGB	VCASSTGBBN	Misc Heinz et al.(2010) Panc1-Ptf1a_GSE47459	0.890	0.981
PTF1A M04157_2.00	Homo sapiens	AMCAGCTGACRB	VYGTCAGCTGKT	SELEX Yin et al.(2017) PTF1A_eDBD_Methyl-HT-SELEX	0.890	0.981
Fer1 M03620_2.00	Drosophila melanogaster	VDCASCTGHY	RDCAGSTGHB	SELEX Nitta et al.(2015) Fer1_1	0.870	0.846
Fer1 M05990_2.00	Drosophila melanogaster	HVCASMTGWCV	BGWCAKSTGBD	B1H Zhu et al.(2011) Fer1_da_SANGER_10_FBgn0037475	0.870	0.846
Fer1 M05991_2.00	Drosophila melanogaster	WYRHCAGCTGACG	CGTCAGCTGDYRW	B1H Zhu et al.(2011) Fer1_SANGER_5_FBgn0037475	0.870	0.846
For this family, TFs with SR scores > 0.838* will likely have a similar motif*