NCBI Gene Info:Enables protein heterodimerization activity. Acts upstream of or within negative regulation of transcription, DNA-templated and somite specification. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including germ ring; margin; mesoderm; presumptive mesoderm; and tail bud. Human ortholog(s) of this gene implicated in spondylocostal dysostosis. Orthologous to human HES7 (hes family bHLH transcription factor 7). [provided by Alliance of Genome Resources, Apr 2022] |