CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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neurod2
(
Danio rerio
)
bHLH
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00010 (HLH)
IPR001092
ENSDARG00000016854
T033646_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in neuron differentiation and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including regulation of neuron differentiation; regulation of synapse maturation; and regulation of transcription, DNA-templated. Predicted to be active in nucleus. Is expressed in granule cell. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 72. Orthologous to human NEUROD2 (neuronal differentiation 2). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
No direct experiments
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
NEUROD2
M02795_2.00
Homo sapiens
RVCATATGKY
RMCATATGBY
SELEX
Jolma et al.(2013)
NEUROD2_1
0.894
0.962
NEUROD2
M04160_2.00
Homo sapiens
RVCATATGKY
RMCATATGBY
SELEX
Yin et al.(2017)
NEUROD2_FL_HT-SELEX
0.894
0.962
NEUROD2
M08737_2.00
Homo sapiens
RRCAGMTGG
CCAKCTGYY
Misc
Kulakovskiy et al.(2013)
NDF2_HUMAN.H11MO.0.B
0.894
0.962
Neurod2
M08770_2.00
Mus musculus
RVCAGATGGB
VCCATCTGBY
Misc
Kulakovskiy et al.(2013)
NDF2_MOUSE.H11MO.0.A
0.894
0.962
NEUROD2
M04161_2.00
Homo sapiens
RMCATATGBY
RVCATATGKY
SELEX
Yin et al.(2017)
NEUROD2_FL_Methyl-HT-SELEX
0.894
0.962
NEUROD1
M04148_2.00
Homo sapiens
RMCATATGKYVNNNTAWTT
AAWTANNNBRMCATATGKY
SELEX
Yin et al.(2017)
NEUROD1_FL_HT-SELEX
0.859
0.923
NEUROD1
M08057_2.00
Homo sapiens
NNVCAGATGGNNN
NNNCCATCTGBNN
ChIP-seq
Mathelier et al.(2014)
MA1109.1
0.859
0.923
NEUROD1
M08735_2.00
Homo sapiens
RVCAGATGGY
RCCATCTGBY
Misc
Kulakovskiy et al.(2013)
NDF1_HUMAN.H11MO.0.A
0.859
0.923
Neurod1
M08764_2.00
Mus musculus
RVCAGATGGY
RCCATCTGBY
Misc
Kulakovskiy et al.(2013)
NDF1_MOUSE.H11MO.0.A
0.859
0.923
Neurod1
M09474_2.00
Mus musculus
RVCAGATGGY
RCCATCTGBY
Misc
Heinz et al.(2010)
Islet-NeuroD1_GSE30298
0.859
0.923
NEUROD1
M09873_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NEUROD_01
0.859
0.923
NEUROD1
M09874_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NEUROD_02
0.859
0.923
NEUROD1
M04149_2.00
Homo sapiens
RVCATATGBYVYNBTAWTW
WAWTAVNRBRVCATATGBY
SELEX
Yin et al.(2017)
NEUROD1_FL_Methyl-HT-SELEX
0.859
0.923
For this family, TFs with SR scores >
0.838
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSDARP00000023642
bHLH
108
160
RRQKANARERTRMHDLNSALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALS
Links
Other
bHLH
family TFs
Other
Danio rerio
TFs
264 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy