CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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tal1
(
Danio rerio
)
bHLH
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00010 (HLH)
IPR001092
ENSDARG00000019930
T033655_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Enables sequence-specific DNA binding activity. Involved in circulatory system development and hemopoiesis. Acts upstream of or within several processes, including animal organ development; positive regulation of endothelial cell differentiation; and vasculogenesis. Predicted to be located in nucleus. Is expressed in several structures, including cardiovascular system; hematopoietic cell; hematopoietic system; mesoderm; and nervous system. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia. Orthologous to human TAL1 (TAL bHLH transcription factor 1, erythroid differentiation factor). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
No direct experiments
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
TAL1
M08734_2.00
Homo sapiens
BSTTATCWSNNNNNNVCVV
BBGBNNNNNNSWGATAASV
Misc
Kulakovskiy et al.(2013)
TAL1_HUMAN.H11MO.0.A
0.914
1.000
Tal1
M08759_2.00
Mus musculus
BYKBNNNNNNVWGATAAVVN
NBBTTATCWBNNNNNNVMRV
Misc
Kulakovskiy et al.(2013)
TAL1_MOUSE.H11MO.0.A
0.914
1.000
Tal1
M09471_2.00
Mus musculus
NVCWKMWG
CWKMWGBN
Misc
Heinz et al.(2010)
HPC7-Scl_GSE13511
0.914
1.000
Tal1
M09472_2.00
Mus musculus
YTATCWSNNNNNNVCAGVHN
NDBCTGBNNNNNNSWGATAR
Misc
Heinz et al.(2010)
Ter119-SCL_GSE18720
0.914
1.000
TAL1
M09870_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TAL1_01
0.914
1.000
TAL1
M09871_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TAL1_Q6_01
0.914
1.000
TAL1
M09872_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TAL1_Q6
0.914
1.000
LYL1
M08714_2.00
Homo sapiens
VNRRNVVCAGMWGN
NCWKCTGBBNYYNB
Misc
Kulakovskiy et al.(2013)
LYL1_HUMAN.H11MO.0.A
0.888
0.885
Lyl1
M08763_2.00
Mus musculus
VNRRNVVCAGMWGN
NCWKCTGBBNYYNB
Misc
Kulakovskiy et al.(2013)
LYL1_MOUSE.H11MO.0.A
0.853
0.865
For this family, TFs with SR scores >
0.838
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSDARP00000077498
bHLH
186
238
RRIFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLA
Links
Other
bHLH
family TFs
Other
Danio rerio
TFs
224 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy