| NCBI Gene Info:Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within nervous system development and proximal tubule development. Predicted to be located in nucleus. Is expressed in several structures, including basal plate midbrain region; central nervous system; corpuscles of Stannius; intermediate mesoderm; and pronephros. Human ortholog(s) of this gene implicated in obesity. Orthologous to human SIM1 (SIM bHLH transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022] |