NCBI Gene Info:Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in heart looping and swim bladder formation. Acts upstream of or within heart development; regulation of neural retina development; and regulation of skeletal muscle cell differentiation. Predicted to be located in cytoplasm and nuclear speck. Predicted to be active in nucleus. Is expressed in several structures, including nervous system; neural crest cell; optic cup; optic vesicle; and trunk. Orthologous to human ATOH8 (atonal bHLH transcription factor 8). [provided by Alliance of Genome Resources, Apr 2022] |