arntl2 (Danio rerio)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSDARG00000041381 T033687_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within circadian rhythm and photoperiodism. Predicted to be located in cytoplasm. Predicted to be part of aryl hydrocarbon receptor complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in hypertension and type 2 diabetes mellitus. Orthologous to human ARNTL2 (aryl hydrocarbon receptor nuclear translocator like 2). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Arntl
M01751_2.00
Mus musculus
NCACGTGAYN

NRTCACGTGN
PBM
Weirauch et al.(2014)
pTH5064
0.839 0.796
ARNTL
M02787_2.00
Homo sapiens
GTCACGTGAC

GTCACGTGAC
SELEX
Jolma et al.(2013)
ARNTL_1
0.839 0.796
ARNTL
M04124_2.00
Homo sapiens
RDCACGTGHN

NDCACGTGHY
SELEX
Yin et al.(2017)
ARNTL_eDBD_HT-SELEX
0.839 0.796
ARNTL
M08725_2.00
Homo sapiens
NVDCACGTGBN

NVCACGTGHBN
Misc
Kulakovskiy et al.(2013)
BMAL1_HUMAN.H11MO.0.A
0.839 0.796
Arntl
M08776_2.00
Mus musculus
VCACGTGMN

NKCACGTGB
Misc
Kulakovskiy et al.(2013)
BMAL1_MOUSE.H11MO.0.A
0.839 0.796
Arntl
M09478_2.00
Mus musculus
CACGTGNN

NNCACGTG
Misc
Heinz et al.(2010)
Liver-Bmal1_GSE39860
0.839 0.796
Arntl
M09889_2.00
Rattus norvegicus Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$BMAL1_01
0.839 0.796
ARNTL
M09841_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$BMAL1_Q6
0.839 0.796
ARNTL
M04125_2.00
Homo sapiens
NDCACRTGHY

RDCAYGTGHN
SELEX
Yin et al.(2017)
ARNTL_eDBD_Methyl-HT-SELEX
0.839 0.796
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSDARP00000134619 bHLH 90 143
ENSDARP00000139384 bHLH 90 143

Links

Other bHLH family TFs
Other Danio rerio TFs

Invalid Input OrderBy

114 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action