epas1b (Danio rerio)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSDARG00000057671 T033709_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables transcription cis-regulatory region binding activity. Acts upstream of or within several processes, including digestive system development; embryonic liver development; and hematopoietic stem cell differentiation. Predicted to be located in nucleus. Is expressed in several structures, including cardiovascular system; digestive system; musculature system; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in familial erythrocytosis 4; lung non-small cell carcinoma; polycythemia; and pulmonary hypertension. Orthologous to human EPAS1 (endothelial PAS domain protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
ENSDARP00000074832 bHLH 15 67

Links

Other bHLH family TFs
Other Danio rerio TFs

24 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSTNIG00000019821 Tetraodon nigroviridis ENSTNIG00000019821 I 0.886
hif1aa Takifugu rubripes ENSTRUG00000012093 N 0.877
Afo_R010338 Aptenodytes forsteri Afo_R010338 I 0.861
Aan_R001655 Calypte anna Aan_R001655 I 0.861
Alligator_sinensis_CCG014229.1 Alligator sinensis Alligator_sinensis_CCG014229.1 I 0.861
Brh_R012268 Buceros rhinoceros Brh_R012268 I 0.861
Tal_R011146 Tyto alba Tal_R011146 I 0.861
Ogr06281 Ophisaurus gracilis Ogr06281 I 0.861
Gfo_R006824 Geospiza fortis Gfo_R006824 I 0.861
Cmyd_10008490 Chelonia mydas Cmyd_10008490 I 0.861
HIF1A Anolis carolinensis ENSACAG00000016205 I 0.861
HIF1A Taeniopygia guttata ENSTGUG00000012978 I 0.861
ENSLOCG00000010146 Lepisosteus oculatus ENSLOCG00000010146 I 0.861
HIF1A Gallus gallus ENSGALG00000011870 I 0.861
ENSFALG00000003396 Ficedula albicollis ENSFALG00000003396 I 0.861
ENSAPLG00000002715 Anas platyrhynchos ENSAPLG00000002715 I 0.861
ENSSHAG00000012129 Sarcophilus harrisii ENSSHAG00000012129 I 0.861
HIF1A Meleagris gallopavo ENSMGAG00000013552 I 0.861
ENSPSIG00000010467 Pelodiscus sinensis ENSPSIG00000010467 I 0.861
HIF1A Monodelphis domestica ENSMODG00000008760 I 0.861
ENSPMAG00000000126 Petromyzon marinus ENSPMAG00000000126 N 0.851
ENSONIG00000020112 Oreochromis niloticus ENSONIG00000020112 N 0.850
e_gw.35.42.1 Branchiostoma floridae e_gw.35.42.1 I 0.839
e_gw.35.150.1 Branchiostoma floridae e_gw.35.150.1 I 0.839