arnt2 (Danio rerio)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSDARG00000103697 T033747_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables DNA-binding transcription factor activity. Involved in regulation of transcription, DNA-templated; response to hypoxia; and signal transduction. Acts upstream of or within several processes, including animal organ development; neuron differentiation; and positive regulation of transcription, DNA-templated. Predicted to be located in cytoplasm. Predicted to be part of aryl hydrocarbon receptor complex. Predicted to be active in nucleus. Is expressed in several structures, including gut; hatching gland; mandibular arch skeleton; nervous system; and vasculature. Orthologous to human ARNT2 (aryl hydrocarbon receptor nuclear translocator 2). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Arnt2
M01720_2.00 		Mus musculus
NCAYRTGMNN
NNKCAYRTGN		 PBM
Weirauch et al.(2014)
pTH5159 		0.914 0.981
ARNT2
M04170_2.00 		Homo sapiens
RDCACGTGMN
NKCACGTGHY		 SELEX
Yin et al.(2017)
ARNT2_eDBD_HT-SELEX 		0.914 1.000
Arnt2
M09888_2.00 		Rattus norvegicus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$ARNT2_01 		0.914 1.000
Arnt
M01719_2.00 		Mus musculus
NNKCACGTGMNN
NNKCACGTGMNN		 PBM
Weirauch et al.(2014)
pTH5111 		0.862 0.963
ARNT
M08732_2.00 		Homo sapiens
NKRCGTGMN
NKCACGYMN		 Misc
Kulakovskiy et al.(2013)
ARNT_HUMAN.H11MO.0.B 		0.862 0.963
ARNT
M09459_2.00 		Homo sapiens
KCACGTNN
NNACGTGM		 Misc
Heinz et al.(2010)
T47D-HIF1b_GSE59937 		0.862 0.963
ARNT
M09863_2.00 		Homo sapiens
NVNNNCACGTGNHHHN
NDDDNCACGTGNNNBN		 Transfac
Matys et al.(2006)
V$ARNT_01 		0.862 0.963
ARNT
M09864_2.00 		Homo sapiens
VVNNNRKCACGTGMYNNNBB
VVNNNRKCACGTGMYNNNBB		 Transfac
Matys et al.(2006)
V$ARNT_02 		0.862 0.963
ARNT
M09865_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$ARNT_Q6_01 		0.862 0.963
ARNT
M09866_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$ARNT_Q6 		0.862 0.944
tgo
M06005_2.00 		Drosophila melanogaster
RDDTCGTGAYY
RRTCACGAHHY		 B1H
Zhu et al.(2011)
dys_tgo_SANGER_5_FBgn0015014 		0.862 0.907
tgo
M06006_2.00 		Drosophila melanogaster
SDTTGCGTGAC
GTCACGCAAHS		 B1H
Zhu et al.(2011)
ss_tgo_SANGER_10_FBgn0015014 		0.862 0.889
tgo
M06007_2.00 		Drosophila melanogaster
KCACGTGAC
GTCACGTGM		 B1H
Zhu et al.(2011)
tgo_cyc_SANGER_5_FBgn0015014 		0.862 0.889
tgo
M06008_2.00 		Drosophila melanogaster
RTACGTGAC
GTCACGTAY		 B1H
Zhu et al.(2011)
tgo_sima_SANGER_5_FBgn0015014 		0.862 0.889
tgo
M06009_2.00 		Drosophila melanogaster
VWACGTGACY
RGTCACGTWB		 B1H
Zhu et al.(2011)
tgo_sim_SANGER_5_FBgn0015014 		0.862 0.889
tgo
M06010_2.00 		Drosophila melanogaster
TGCGTGAC
GTCACGCA		 B1H
Zhu et al.(2011)
tgo_ss_SANGER_5_FBgn0015014 		0.862 0.889
tgo
M06011_2.00 		Drosophila melanogaster
RCACGTGAC
GTCACGTGY		 B1H
Zhu et al.(2011)
tgo_tai_SANGER_5_FBgn0015014 		0.862 0.889
tgo
M06012_2.00 		Drosophila melanogaster
VTACGTGACB
VGTCACGTAB		 B1H
Zhu et al.(2011)
tgo_trh_SANGER_5_FBgn0015014 		0.862 0.907
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSDARP00000131184 bHLH 79 132
ENSDARP00000131846 bHLH 64 117
ENSDARP00000136894 bHLH 79 132

Links

Other bHLH family TFs
Other Danio rerio TFs

Invalid Input OrderBy

176 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action