MAX (Homo sapiens)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSG00000125952 T034282_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
MAX
M00938_2.00		 Homo sapiens
CCACGTGH
DCACGTGG		 PBM
Guo et al.(2014)
Max_L		 (Direct) (Direct)
MAX
M01497_2.00		 Homo sapiens
NCRCATGNN
NNCATGYGN		 PBM
Yin et al.(2017b)
MAX_5mCG		 (Direct) (Direct)
MAX
M01498_2.00		 Homo sapiens
NCRCRTGN
NCAYGYGN		 PBM
Yin et al.(2017b)
MAX_Cytosine		 (Direct) (Direct)
MAX
M02785_2.00		 Homo sapiens
CACGTGNHNNNCACGTG
CACGTGNNNDNCACGTG		 SELEX
Jolma et al.(2013)
MAX_1		 (Direct) (Direct)
MAX
M02786_2.00		 Homo sapiens
VVCACGTGNN
NNCACGTGBB		 SELEX
Jolma et al.(2013)
MAX_2		 (Direct) (Direct)
MAX
M04112_2.00		 Homo sapiens
NCACGTGNNNNNCACGTGN
NCACGTGNNNNNCACGTGN		 SELEX
Yin et al.(2017)
MAX_eDBD_HT-SELEX		 (Direct) (Direct)
MAX
M04113_2.00		 Homo sapiens
BCACRTGBHNNBCACATGK
MCATGTGVNNDVCAYGTGV		 SELEX
Yin et al.(2017)
MAX_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)
MAX
M04114_2.00		 Homo sapiens
NVCACGTGNB
VNCACGTGBN		 SELEX
Yin et al.(2017)
MAX_FL_HT-SELEX		 (Direct) (Direct)
MAX
M04115_2.00		 Homo sapiens
NNCACRTGBN
NVCAYGTGNN		 SELEX
Yin et al.(2017)
MAX_FL_Methyl-HT-SELEX		 (Direct) (Direct)
MAX
M05832_2.00		 Homo sapiens
CACGTG
CACGTG		 SMiLE-seq
Isakova et al.(2017)
MAX		 (Direct) (Direct)
MAX
M07791_2.00		 Homo sapiens
SNBCACGTGNYHN
NDRNCACGTGVNS		 ChIP-seq
Gerstein et al.(2012)
GM12878_MAX_Stanford		 (Direct) (Direct)
MAX
M07792_2.00		 Homo sapiens
NVRVCACGTGS
SCACGTGBYBN		 ChIP-seq
Gerstein et al.(2012)
H1-hESC_MAX_UCD		 (Direct) (Direct)
MAX
M07793_2.00		 Homo sapiens
DSCACGTGKBN
NVMCACGTGSH		 ChIP-seq
Gerstein et al.(2012)
HeLa-S3_MAX_Stanford		 (Direct) (Direct)
MAX
M07794_2.00		 Homo sapiens
NRRBCACGTGVNS
SNBCACGTGVYYN		 ChIP-seq
Gerstein et al.(2012)
HUVEC_MAX_Stanford		 (Direct) (Direct)
MAX
M07795_2.00		 Homo sapiens
VVVCACGTGS
SCACGTGBBB		 ChIP-seq
Gerstein et al.(2012)
K562_MAX_HudsonAlpha		 (Direct) (Direct)
MAX
M07796_2.00		 Homo sapiens
BCACGTGVYY
RRBCACGTGV		 ChIP-seq
Gerstein et al.(2012)
K562_MAX_Stanford		 (Direct) (Direct)
MAX
M07797_2.00		 Homo sapiens
VCACGTGNYYN
NRRNCACGTGB		 ChIP-seq
Gerstein et al.(2012)
NB4_MAX_Stanford		 (Direct) (Direct)
MAX
M08723_2.00		 Homo sapiens
VNSCACGTGD
HCACGTGSNB		 Misc
Kulakovskiy et al.(2013)
MAX_HUMAN.H11MO.0.A		 (Direct) (Direct)
MAX
M09835_2.00		 Homo sapiens
NDRNCACGTGNYHN
NDRNCACGTGNYHN		 Transfac
Matys et al.(2006)
V$MAX_01		 (Direct) (Direct)
MAX
M09836_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MAX_11		 (Direct) (Direct)
MAX
M09837_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MAX_Q6		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Max
M00121_2.00 		Mus musculus
NCRCRTGNN
NNCAYGYGN		 PBM
Badis et al.(2009)
Max_3863 		0.914 1.000
Max
M00122_2.00 		Mus musculus
NNCRCRTGN
NCAYGYGNN		 PBM
Badis et al.(2009)
Max_3864 		0.914 1.000
Max
M01753_2.00 		Mus musculus
NCAYGYKNN
NNMRCRTGN		 PBM
Weirauch et al.(2014)
pTH4381 		0.914 1.000
Max
M08778_2.00 		Mus musculus
VVVCACGYGSN
NSCRCGTGBBB		 Misc
Kulakovskiy et al.(2013)
MAX_MOUSE.H11MO.0.A 		0.914 1.000
For this family, TFs with SR scores > 0.838 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00938_2.00 bHLH 24 75
M01497_2.00 bHLH 22 73
M01498_2.00 bHLH 22 73

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000246163 bHLH 24 59
ENSP00000284165 bHLH 24 75
ENSP00000342482 bHLH 24 63
ENSP00000351175 bHLH 15 66
ENSP00000351490 bHLH 24 75
ENSP00000378104 bHLH 24 75
ENSP00000450818 bHLH 15 66
ENSP00000451907 bHLH 24 75
ENSP00000452197 bHLH 15 66
ENSP00000452286 bHLH 15 66
ENSP00000452378 bHLH 24 75
ENSP00000452405 bHLH 16 39
ENSP00000480127 bHLH 24 75

Links

Other bHLH family TFs
Other Homo sapiens TFs

Invalid Input OrderBy

118 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action