CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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ATOH7
(
Homo sapiens
)
bHLH
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00010 (HLH)
IPR001092
ENSG00000179774
T034327_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
This intronless gene encodes a member of the basic helix-loop-helix family of transcription factors, with similarity to Drosophila atonal gene that controls photoreceptor development. Studies in mice suggest that this gene plays a central role in retinal ganglion cell and optic nerve formation. Mutations in this gene are associated with nonsyndromic congenital retinal nonattachment. [provided by RefSeq, Dec 2011]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
ATOH7
M04193_2.00
Homo sapiens
AVCATATGBY
RVCATATGBT
SELEX
Yin et al.(2017)
ATOH7_eDBD_HT-SELEX
(Direct)
(Direct)
ATOH7
M04194_2.00
Homo sapiens
AVCATATGKY
RMCATATGBT
SELEX
Yin et al.(2017)
ATOH7_eDBD_Methyl-HT-SELEX
(Direct)
(Direct)
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
For this family, TFs with SR scores >
0.838
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSP00000362777
bHLH
41
93
RRLAANARERRRMQGLNTAFDRLRRVVPQWGQDKKLSKYETLQMALSYIMALT
Links
Other
bHLH
family TFs
Other
Homo sapiens
TFs
59 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy