Mnt (Mus musculus)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSMUSG00000000282 T035654_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables DNA binding activity; DNA-binding transcription factor activity; and chromatin binding activity. Acts upstream of or within several processes, including cell aging; negative regulation of apoptotic signaling pathway; and regulation of transcription, DNA-templated. Predicted to be located in nucleoplasm. Is expressed in several structures, including central nervous system; early conceptus; future brain; genitourinary system; and retina nuclear layer. Used to study Miller-Dieker lissencephaly syndrome. Orthologous to human MNT (MAX network transcriptional repressor). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Mnt
M01716_2.00
Mus musculus
NCACGTGNN

NNCACGTGN
PBM
Weirauch et al.(2014)
pTH4588
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
MNT
M02774_2.00
Homo sapiens
NVCACGTGNH

DNCACGTGBN
SELEX
Jolma et al.(2013)
MNT_1
0.914 1.000
For this family, TFs with SR scores > 0.838 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M01716_2.00 bHLH 16 67

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000000291 bHLH 223 274
ENSMUSP00000118435 bHLH 1 42

Links

Other bHLH family TFs
Other Mus musculus TFs

Invalid Input OrderBy

71 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action