Hey2 (Mus musculus)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSMUSG00000019789 T035670_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Hey2
M01722_2.00
Mus musculus
RCACGTGNN

NNCACGTGY
PBM
Weirauch et al.(2014)
pTH5102
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
HEY2
M02790_2.00
Homo sapiens
GRCACGTGNV

BNCACGTGYC
SELEX
Jolma et al.(2013)
HEY2_1
0.914 1.000
HEY2
M02791_2.00
Homo sapiens
GVCACGTGYN

NRCACGTGBC
SELEX
Jolma et al.(2013)
HEY2_2
0.914 1.000
HEY2
M04131_2.00
Homo sapiens
NVCRCGYGVN

NBCRCGYGBN
SELEX
Yin et al.(2017)
HEY2_eDBD_HT-SELEX
0.914 1.000
HEY2
M04133_2.00
Homo sapiens
NVCACGTGVN

NBCACGTGBN
SELEX
Yin et al.(2017)
HEY2_FL_HT-SELEX
0.914 1.000
HEY2
M04132_2.00
Homo sapiens
NVCRCGYRVN

NBYRCGYGBN
SELEX
Yin et al.(2017)
HEY2_eDBD_Methyl-HT-SELEX
0.914 1.000
HEY2
M04134_2.00
Homo sapiens
NVCRCGYGSN

NSCRCGYGBN
SELEX
Yin et al.(2017)
HEY2_FL_Methyl-HT-SELEX
0.914 1.000
For this family, TFs with SR scores > 0.838 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M01722_2.00 bHLH 13 68

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000019924 bHLH 49 104

Links

Other bHLH family TFs
Other Mus musculus TFs

163 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ENSLOCG00000017268 Lepisosteus oculatus ENSLOCG00000017268 I 0.914
HEY2 Echinops telfairi ENSETEG00000007340 I 0.914
ENSNLEG00000013972 Nomascus leucogenys ENSNLEG00000013972 I 0.914
ENSFALG00000011461 Ficedula albicollis ENSFALG00000011461 I 0.914
HEY2 Vicugna pacos ENSVPAG00000010498 I 0.914
HEY2 Erinaceus europaeus ENSEEUG00000014040 I 0.914
HEY2 Meleagris gallopavo ENSMGAG00000013281 I 0.914
HEY2 Dasypus novemcinctus ENSDNOG00000044967 I 0.914
Afo_R005555 Aptenodytes forsteri Afo_R005555 I 0.914
ENSDORG00000009001 Dipodomys ordii ENSDORG00000009001 I 0.914
Aan_R009606 Calypte anna Aan_R009606 I 0.914
HEY2 Equus caballus ENSECAG00000014094 I 0.914
ENSPPYG00000016987 Pongo abelii ENSPPYG00000016987 I 0.914
HEY2 Felis catus ENSFCAG00000026914 I 0.914
ENSSHAG00000016487 Sarcophilus harrisii ENSSHAG00000016487 I 0.914
ENSPSIG00000012495 Pelodiscus sinensis ENSPSIG00000012495 I 0.914
HEY2 Sorex araneus ENSSARG00000011755 I 0.914
Hey2 Rattus norvegicus ENSRNOG00000013364 I 0.914
HEY2 Pan troglodytes ENSPTRG00000018574 I 0.914
HEY2 Sus scrofa ENSSSCG00000004223 I 0.914
HEY2 Loxodonta africana ENSLAFG00000014208 I 0.914
HEY2 Homo sapiens ENSG00000135547 D 0.914
HEY2 Taeniopygia guttata ENSTGUG00000011792 I 0.914
HEY2 Tupaia belangeri ENSTBEG00000008836 I 0.914
ENSSTOG00000022371 Ictidomys tridecemlineatus ENSSTOG00000022371 I 0.914
Alligator_sinensis_CCG009102.1 Alligator sinensis Alligator_sinensis_CCG009102.1 I 0.914
HEY2 Myotis lucifugus ENSMLUG00000002617 I 0.914
ENSAPLG00000003195 Anas platyrhynchos ENSAPLG00000003195 I 0.914
ENSAMXG00000018013 Astyanax mexicanus ENSAMXG00000018013 I 0.914
Ogr15033 Ophisaurus gracilis Ogr15033 I 0.914
HEY2 Bos taurus ENSBTAG00000000919 I 0.914
Myotis_brandtii_hey2_10035635 Myotis brandtii Myotis_brandtii_hey2_10035635 I 0.914
Pvit_01735 Pogona vitticeps Pvit_01735 I 0.914
ENSMPUG00000014531 Mustela putorius furo ENSMPUG00000014531 I 0.914
ENSOANG00000022119 Ornithorhynchus anatinus ENSOANG00000022119 I 0.914
hey2 Xenopus tropicalis XB-GENE-485923 I 0.914
ENSOARG00000007915 Ovis aries ENSOARG00000007915 I 0.914
HEY2 Anolis carolinensis ENSACAG00000001813 I 0.914
ENSAMEG00000009592 Ailuropoda melanoleuca ENSAMEG00000009592 I 0.914
ENSLACG00000006098 Latimeria chalumnae ENSLACG00000006098 I 0.914
Gfo_R016187 Geospiza fortis Gfo_R016187 I 0.914
HEY2 Macaca mulatta ENSMMUG00000009491 I 0.914
Cmyd_10006677 Chelonia mydas Cmyd_10006677 I 0.914
ENSCSAG00000016312 Chlorocebus sabaeus ENSCSAG00000016312 I 0.914
hey2 Danio rerio ENSDARG00000013441 I 0.914
Brh_R011837 Buceros rhinoceros Brh_R011837 I 0.914
HEY2 Monodelphis domestica ENSMODG00000017701 I 0.914
HEY2 Cavia porcellus ENSCPOG00000021417 I 0.914
HEY2 Otolemur garnettii ENSOGAG00000027812 I 0.914
ENSCAFG00000032212 Canis familiaris ENSCAFG00000032212 I 0.914
HEY2 Callithrix jacchus ENSCJAG00000003761 I 0.914
ENSP00000357348 Macaca fascicularis ENSP00000357348 I 0.914
ENSP00000357348-D1 Bos grunniens ENSP00000357348-D1 I 0.914
ENSLACG00000012215 Latimeria chalumnae ENSLACG00000012215 I 0.890
ISCW011251 Ixodes scapularis ISCW011251 I 0.890
CGI_10018323 Crassostrea gigas CGI_10018323 I 0.890
Ocbimv22039104m.g Octopus bimaculoides Ocbimv22039104m.g I 0.890
estExt_GenewiseH_1.C_4620016 Branchiostoma floridae estExt_GenewiseH_1.C_4620016 I 0.887
ENSONIG00000018772 Oreochromis niloticus ENSONIG00000018772 I 0.886
ENSOCUG00000029649 Oryctolagus cuniculus ENSOCUG00000029649 I 0.871
HEYL Oryctolagus cuniculus ENSOCUG00000000560 I 0.870
ENSP00000361943 Macaca fascicularis ENSP00000361943 I 0.870
ENSSSCG00000024651 Sus scrofa ENSSSCG00000024651 I 0.870
ENSSHAG00000018213 Sarcophilus harrisii ENSSHAG00000018213 I 0.870
HEYL Ornithorhynchus anatinus ENSOANG00000010000 I 0.870
HEYL Pan troglodytes ENSPTRG00000000574 I 0.870
ENSP00000361943-D1 Bos grunniens ENSP00000361943-D1 I 0.870
HEYL Otolemur garnettii ENSOGAG00000030877 I 0.870
ENSPANG00000006227 Papio anubis ENSPANG00000006227 I 0.870
L798_14068 Zootermopsis nevadensis L798_14068 I 0.870
ENSPPYG00000001505 Pongo abelii ENSPPYG00000001505 I 0.870
PHUM454530 Pediculus humanus PHUM454530 I 0.870
Alligator_sinensis_CCG011017.1 Alligator sinensis Alligator_sinensis_CCG011017.1 I 0.870
Cmyd_10005434 Chelonia mydas Cmyd_10005434 I 0.870
Heyl Rattus norvegicus ENSRNOG00000015318 I 0.870
HEYL Tursiops truncatus ENSTTRG00000014353 I 0.870
ENSOARG00000020088 Ovis aries ENSOARG00000020088 I 0.870
HEYL Loxodonta africana ENSLAFG00000027563 I 0.870
HEYL Homo sapiens ENSG00000163909 I 0.870
PABPC4 Canis familiaris ENSCAFG00000003081 I 0.870
ENSMEUG00000007444 Macropus eugenii ENSMEUG00000007444 I 0.870
ENSCSAG00000001134 Chlorocebus sabaeus ENSCSAG00000001134 I 0.870
HEYL Dasypus novemcinctus ENSDNOG00000010392 I 0.870
ENSFALG00000000542 Ficedula albicollis ENSFALG00000000542 I 0.870
ENSGALG00000021593 Gallus gallus ENSGALG00000021593 I 0.870
HEYL Gorilla gorilla ENSGGOG00000008268 I 0.870
HEYL Equus caballus ENSECAG00000007220 I 0.870
HEYL Bos taurus ENSBTAG00000008688 I 0.870
ENSCPOG00000000704 Cavia porcellus ENSCPOG00000000704 I 0.870
ENSAPLG00000007121 Anas platyrhynchos ENSAPLG00000007121 I 0.870
Heyl Mus musculus ENSMUSG00000032744 I 0.870
ENSAMEG00000011612 Ailuropoda melanoleuca ENSAMEG00000011612 I 0.870
HEYL Macaca mulatta ENSMMUG00000018861 I 0.870
ENSMPUG00000014412 Mustela putorius furo ENSMPUG00000014412 I 0.870
Sakowv30023592m.g Saccoglossus kowalevskii Sakowv30023592m.g I 0.860
HEY1 Equus caballus ENSECAG00000017010 I 0.860
SPU_009465 Strongylocentrotus purpuratus SPU_009465 I 0.860
hey1 Xenopus tropicalis XB-GENE-486694 I 0.860
hey1.S Xenopus laevis XB-GENE-865637 I 0.860
ENSNLEG00000002239 Nomascus leucogenys ENSNLEG00000002239 I 0.860
HEY1 Takifugu rubripes ENSTRUG00000013573 I 0.860
HEY1 Felis catus ENSFCAG00000025542 I 0.860
ENSFALG00000008605 Ficedula albicollis ENSFALG00000008605 I 0.860
Afo_R005157 Aptenodytes forsteri Afo_R005157 I 0.860
hey1 Danio rerio ENSDARG00000070538 I 0.860
HEY1 Canis familiaris ENSCAFG00000008391 I 0.860
Ogr14041 Ophisaurus gracilis Ogr14041 I 0.860
Gfo_R007552 Geospiza fortis Gfo_R007552 I 0.860
HEY1 Bos taurus ENSBTAG00000015717 I 0.860
HEY1 Cavia porcellus ENSCPOG00000008527 I 0.860
Pvit_00065 Pogona vitticeps Pvit_00065 I 0.860
Myotis_brandtii_HEY1_10021379 Myotis brandtii Myotis_brandtii_HEY1_10021379 I 0.860
Brh_R005579 Buceros rhinoceros Brh_R005579 I 0.860
ENSCSAG00000013410 Chlorocebus sabaeus ENSCSAG00000013410 I 0.860
HEY1 Dasypus novemcinctus ENSDNOG00000031981 I 0.860
HEY1 Tetraodon nigroviridis ENSTNIG00000018401 I 0.860
ENSPSIG00000003791 Pelodiscus sinensis ENSPSIG00000003791 I 0.860
ENSPPYG00000018693 Pongo abelii ENSPPYG00000018693 I 0.860
ENSPFOG00000001913 Poecilia formosa ENSPFOG00000001913 I 0.860
HEY1 Loxodonta africana ENSLAFG00000011488 I 0.860
HEY1 Homo sapiens ENSG00000164683 D 0.860
Hey1 Rattus norvegicus ENSRNOG00000011593 I 0.860
ENSGMOG00000017811 Gadus morhua ENSGMOG00000017811 I 0.860
ENSPANG00000018687 Papio anubis ENSPANG00000018687 I 0.860
HEY1 Oryzias latipes ENSORLG00000008268 I 0.860
ENSOARG00000008063 Ovis aries ENSOARG00000008063 I 0.860
Hey1 Mus musculus ENSMUSG00000040289 I 0.860
ENSMPUG00000001859 Mustela putorius furo ENSMPUG00000001859 I 0.860
HEY1 Otolemur garnettii ENSOGAG00000007210 I 0.860
ENSONIG00000003087 Oreochromis niloticus ENSONIG00000003087 I 0.860
HEY1 Monodelphis domestica ENSMODG00000006648 I 0.860
ENSGMOG00000013488 Gadus morhua ENSGMOG00000013488 I 0.860
ENSLACG00000015540 Latimeria chalumnae ENSLACG00000015540 I 0.860
ENSSHAG00000017958 Sarcophilus harrisii ENSSHAG00000017958 I 0.860
HEY1 Sus scrofa ENSSSCG00000006159 I 0.860
HEY1 Gorilla gorilla ENSGGOG00000009960 I 0.860
ENSSTOG00000023191 Ictidomys tridecemlineatus ENSSTOG00000023191 I 0.860
HEY1 Gasterosteus aculeatus ENSGACG00000008712 I 0.860
hey1 Gasterosteus aculeatus ENSGACG00000003436 I 0.860
hey1 Takifugu rubripes ENSTRUG00000014561 I 0.857
Aqu1.218726 Amphimedon queenslandica Aqu1.218726 I 0.857
hey1 Tetraodon nigroviridis ENSTNIG00000017785 I 0.857
HEYL Myotis lucifugus ENSMLUG00000029490 I 0.845
heyl Tetraodon nigroviridis ENSTNIG00000009228 I 0.840
ENSONIG00000004726 Oreochromis niloticus ENSONIG00000004726 I 0.840
heyl Takifugu rubripes ENSTRUG00000003399 I 0.840
ENSAMXG00000011237 Astyanax mexicanus ENSAMXG00000011237 I 0.840
LDEC001043 Leptinotarsa decemlineata LDEC001043 I 0.840
CapteG228069 Capitella teleta CapteG228069 I 0.840
CapteG182542 Capitella teleta CapteG182542 I 0.840
HEYL Felis catus ENSFCAG00000010963 I 0.840
LotgiG171867 Lottia gigantea LotgiG171867 I 0.840
heyl Danio rerio ENSDARG00000055798 I 0.840
TC001593 Tribolium castaneum TC001593 I 0.840
ENSGMOG00000011084 Gadus morhua ENSGMOG00000011084 I 0.840
YQE_09192 Dendroctonus ponderosae YQE_09192 I 0.840
ENSXMAG00000014241 Xiphophorus maculatus ENSXMAG00000014241 I 0.840
ENSLOCG00000001853 Lepisosteus oculatus ENSLOCG00000001853 I 0.840
heyl Oryzias latipes ENSORLG00000013651 I 0.840
tetur01g03020 Tetranychus urticae tetur01g03020 I 0.840
ENSXMAG00000006950 Xiphophorus maculatus ENSXMAG00000006950 I 0.840
ENSPFOG00000015536 Poecilia formosa ENSPFOG00000015536 I 0.840
heyl Gasterosteus aculeatus ENSGACG00000007492 I 0.840