Tcf3 (Mus musculus)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSMUSG00000020167 T035673_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Tcf3
M00118_2.00		 Mus musculus
VCAYCTGB
VCAGRTGB		 PBM
Badis et al.(2009)
Tcfe2a_3865		 (Direct) (Direct)
Tcf3
M00753_2.00		 Mus musculus
VCACCTGBN
NVCAGGTGB		 PBM
Weirauch et al.(2013)
pTH3866		 (Direct) (Direct)
Tcf3
M01723_2.00		 Mus musculus
NNVCACSTGB
VCASGTGBNN		 PBM
Weirauch et al.(2014)
pTH4580		 (Direct) (Direct)
Tcf3
M09465_2.00		 Mus musculus
ABWTCAAAGS
SCTTTGAWVT		 Misc
Heinz et al.(2010)
mES-Tcf3_GSE11724		 (Direct) (Direct)
Tcf3
M09466_2.00		 Mus musculus
VCAGCTGBNN
NNVCAGCTGB		 Misc
Heinz et al.(2010)
proBcell-E2A_GSE21978		 (Direct) (Direct)
Tcf3
M09886_2.00		 Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E47_05		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Tcf12
M01740_2.00 		Mus musculus
NVCAYCTGB
VCAGRTGBN		 PBM
Weirauch et al.(2014)
pTH5071 		0.914 0.885
TCF12
M04137_2.00 		Homo sapiens
VCACSTGB
VCASGTGB		 SELEX
Yin et al.(2017)
TCF12_eDBD_HT-SELEX 		0.914 0.885
Tcf12
M08062_2.00 		Mus musculus
RRCAGCTGNNN
NNNCAGCTGYY		 ChIP-seq
Mathelier et al.(2014)
MA0521.1 		0.886 0.962
TCF12
M07805_2.00 		Homo sapiens
NVDSCAGSTGB
VCASCTGSHBN		 ChIP-seq
Gerstein et al.(2012)
GM12878_TCF12_HudsonAlpha 		0.886 0.962
TCF12
M07806_2.00 		Homo sapiens
VCASCTGB
VCAGSTGB		 ChIP-seq
Gerstein et al.(2012)
H1-hESC_TCF12_HudsonAlpha 		0.886 0.962
TCF12
M08731_2.00 		Homo sapiens
CMCASCTGSH
DSCAGSTGKG		 Misc
Kulakovskiy et al.(2013)
HTF4_HUMAN.H11MO.0.A 		0.886 0.962
Tcf12
M08762_2.00 		Mus musculus
VMCASCTGSH
DSCAGSTGKB		 Misc
Kulakovskiy et al.(2013)
HTF4_MOUSE.H11MO.0.A 		0.886 0.962
TCF12
M09458_2.00 		Homo sapiens
NNVCAGCTGB
VCAGCTGBNN		 Misc
Heinz et al.(2010)
GM12878-Tcf12_GSE32465 		0.914 0.885
TCF12
M09858_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HEB_Q6 		0.914 0.885
TCF12
M09859_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HTF4_Q2 		0.914 0.885
TCF12
M09860_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TCF12_01 		0.886 0.962
TCF12
M09861_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TCF12_03 		0.886 0.962
TCF12
M09862_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TCF12_05 		0.886 0.962
TCF12
M04138_2.00 		Homo sapiens
NCAYCTGN
NCAGRTGN		 SELEX
Yin et al.(2017)
TCF12_eDBD_Methyl-HT-SELEX 		0.886 0.962
TCF3
M02775_2.00 		Homo sapiens
NVCACCTGBN
NVCAGGTGBN		 SELEX
Jolma et al.(2013)
TCF3_1 		0.886 0.942
Tcf4
M01750_2.00 		Mus musculus
VCAGVTGBN
NVCABCTGB		 PBM
Weirauch et al.(2014)
pTH5101 		0.912 0.885
TCF4
M02807_2.00 		Homo sapiens
HRCACCTGBN
NVCAGGTGYD		 SELEX
Jolma et al.(2013)
TCF4_1 		0.912 0.885
TCF3
M08710_2.00 		Homo sapiens
VVCASCTGCHN
NDGCAGSTGBB		 Misc
Kulakovskiy et al.(2013)
TFE2_HUMAN.H11MO.0.A 		0.886 0.942
TCF4
M02808_2.00 		Homo sapiens
NVCACCTBBN
NVVAGGTGBN		 SELEX
Jolma et al.(2013)
TCF4_2 		0.912 0.885
TCF3
M09791_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E12_Q6 		0.886 0.942
TCF4
M02728_2.00 		Homo sapiens
RCACCTG
CAGGTGY		 SELEX
Jolma et al.(2010)
TCF4_dimer 		0.912 0.885
TCF3
M09792_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2A_Q6_01 		0.886 0.942
TCF3
M09793_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2A_Q6_02 		0.886 0.942
TCF4
M04214_2.00 		Homo sapiens
VCACCTGB
VCAGGTGB		 SELEX
Yin et al.(2017)
TCF4_eDBD_HT-SELEX 		0.912 0.885
TCF3
M09794_2.00 		Homo sapiens
VVVVMCACCTGCNBB
VVNGCAGGTGKBBBB		 Transfac
Matys et al.(2006)
V$E47_01 		0.886 0.942
Tcf4
M08775_2.00 		Mus musculus
HRCACCTGB
VCAGGTGYD		 Misc
Kulakovskiy et al.(2013)
ITF2_MOUSE.H11MO.0.B 		0.912 0.885
TCF3
M09795_2.00 		Homo sapiens
NNKWRCACCTGYDNNN
NNNHRCAGGTGYWMNN		 Transfac
Matys et al.(2006)
V$E47_02 		0.886 0.942
TCF4
M09461_2.00 		Homo sapiens
ASWTCAAAGRVN
NBYCTTTGAWST		 Misc
Heinz et al.(2010)
Hct116-Tcf4_SRA012054 		0.912 0.885
TCF4
M04215_2.00 		Homo sapiens
VCACCTGN
NCAGGTGB		 SELEX
Yin et al.(2017)
TCF4_eDBD_Methyl-HT-SELEX 		0.912 0.885
For this family, TFs with SR scores > 0.838 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00118_2.00 bHLH 101 154
M00753_2.00 bHLH 16 69
M01723_2.00 bHLH 16 69

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000020377 bHLH 548 601
ENSMUSP00000020379 bHLH 545 598
ENSMUSP00000100976 bHLH 544 597
ENSMUSP00000100977 bHLH 544 597
ENSMUSP00000100978 bHLH 541 594
ENSMUSP00000100979 bHLH 549 602
ENSMUSP00000100980 bHLH 545 598
ENSMUSP00000100981 bHLH 546 599
ENSMUSP00000100982 bHLH 544 597
ENSMUSP00000100983 bHLH 547 600
ENSMUSP00000121172 bHLH 534 587

Links

Other bHLH family TFs
Other Mus musculus TFs

Invalid Input OrderBy

213 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action