TF Information

Bhlhe22 *(Mus musculus)* bHLH
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF00010 (HLH)	IPR001092	ENSMUSG00000025128	T035686_2.00	Ensembl (2018-Dec-8)	Link out
NCBI Gene Info: Enables DNA-binding transcription factor activity, RNA polymerase II-specific; chromatin binding activity; and identical protein binding activity. Acts upstream of or within cerebral cortex regionalization; negative regulation of transcription, DNA-templated; and neuron differentiation. Located in nucleus. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human BHLHE22 (basic helix-loop-helix family member e22). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
Bhlhe22 M01729_2.00	Mus musculus	NVCATATGGN	NCCATATGBN	PBM Weirauch et al.(2014) pTH5267	(Direct)	(Direct)
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
BHLHE22 M02804_2.00	Homo sapiens	NAVCATATGBTN	NAVCATATGBTN	SELEX Jolma et al.(2013) BHLHE22_1	0.914	1.000
BHLHE22 M04199_2.00	Homo sapiens	AVCATATGBY	RVCATATGBT	SELEX Yin et al.(2017) BHLHE22_eDBD_HT-SELEX	0.914	1.000
BHLHE22 M04200_2.00	Homo sapiens	AVCATATGBY	RVCATATGBT	SELEX Yin et al.(2017) BHLHE22_eDBD_Methyl-HT-SELEX	0.914	1.000
BHLHE23 M02784_2.00	Homo sapiens	RVCATATGBY	RVCATATGBY	SELEX Jolma et al.(2013) BHLHE23_1	0.914	0.963
BHLHE23 M04108_2.00	Homo sapiens	AVCATATGBY	RVCATATGBT	SELEX Yin et al.(2017) BHLHE23_eDBD_HT-SELEX	0.914	0.963
BHLHE23 M04110_2.00	Homo sapiens	RVCATATGBY	RVCATATGBY	SELEX Yin et al.(2017) BHLHE23_FL_HT-SELEX	0.914	0.963
BHLHE23 M04109_2.00	Homo sapiens	AVCATATGBY	RVCATATGBT	SELEX Yin et al.(2017) BHLHE23_eDBD_Methyl-HT-SELEX	0.914	0.963
BHLHE23 M04111_2.00	Homo sapiens	RVCATATGBY	RVCATATGBY	SELEX Yin et al.(2017) BHLHE23_FL_Methyl-HT-SELEX	0.914	0.963
Oli M03618_2.00	Drosophila melanogaster	AMCATATGKY	RMCATATGKT	SELEX Nitta et al.(2015) Oli_1	0.890	0.963
Oli M05985_2.00	Drosophila melanogaster	SACCATATGKY	RMCATATGGTS	B1H Zhu et al.(2011) Oli_da_SANGER_5_1_FBgn0032651	0.890	0.963
Oli M05986_2.00	Drosophila melanogaster	AHSBNRCCATMTGKY	RMCAKATGGYNVSDT	B1H Zhu et al.(2011) Oli_da_SANGER_5_2_FBgn0032651	0.890	0.963
Oli M05987_2.00	Drosophila melanogaster	MCATCTGKY	RMCAGATGK	B1H Zhu et al.(2011) Oli_da_SANGER_5_3_FBgn0032651	0.890	0.963
For this family, TFs with SR scores > 0.838* will likely have a similar motif*