Hes2 (Mus musculus)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSMUSG00000028940 T035697_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
The protein encoded by this gene belongs to the mammalian Hes gene family, the mammalian homologues of Drosophila hairy and Enhancer of split. Hes 2 is a basic helix-loop-helix transcriptional repressor and is an effector of the Notch signaling pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Hes2
M01734_2.00		 Mus musculus
NCACGTKYCNNNN
NNNNGRMACGTGN		 PBM
Weirauch et al.(2014)
pTH5259		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.838 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M01734_2.00 bHLH 13 69

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000030782 bHLH 14 70

Links

Other bHLH family TFs
Other Mus musculus TFs

Invalid Input OrderBy

2 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action