Atoh7 (Mus musculus)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSMUSG00000036816 T035715_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in entrainment of circadian clock by photoperiod. Acts upstream of or within circadian rhythm; entrainment of circadian clock; and neural retina development. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; dorsal root ganglion; early conceptus; eye; and genitourinary system. Human ortholog(s) of this gene implicated in persistent hyperplastic primary vitreous. Orthologous to human ATOH7 (atonal bHLH transcription factor 7). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ATOH7
M04193_2.00 		Homo sapiens
AVCATATGBY
RVCATATGBT		 SELEX
Yin et al.(2017)
ATOH7_eDBD_HT-SELEX 		0.914 0.981
ATOH7
M04194_2.00 		Homo sapiens
AVCATATGKY
RMCATATGBT		 SELEX
Yin et al.(2017)
ATOH7_eDBD_Methyl-HT-SELEX 		0.914 0.981
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000039801 bHLH 42 94

Links

Other bHLH family TFs
Other Mus musculus TFs

Invalid Input OrderBy

59 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action