NCBI Gene Info:Enables DNA binding activity and protein heterodimerization activity. Acts upstream of or within embryonic pattern specification; lung development; and negative regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including branchial arch; future brain; genitourinary system; limb; and musculoskeletal system. Orthologous to human SIM2 (SIM bHLH transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022] |