Atoh7 (Rattus norvegicus)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSRNOG00000000384 T037161_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in entrainment of circadian clock by photoperiod; neuron differentiation; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including entrainment of circadian clock; neural retina development; and optic nerve development. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in persistent hyperplastic primary vitreous. Orthologous to human ATOH7 (atonal bHLH transcription factor 7). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ATOH7
M04193_2.00 		Homo sapiens
AVCATATGBY
RVCATATGBT		 SELEX
Yin et al.(2017)
ATOH7_eDBD_HT-SELEX 		0.914 0.981
ATOH7
M04194_2.00 		Homo sapiens
AVCATATGKY
RMCATATGBT		 SELEX
Yin et al.(2017)
ATOH7_eDBD_Methyl-HT-SELEX 		0.914 0.981
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSRNOP00000000432 bHLH 42 94

Links

Other bHLH family TFs
Other Rattus norvegicus TFs

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59 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action