Hand1 (Rattus norvegicus)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSRNOG00000002582 T037166_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; bHLH transcription factor binding activity; and protein homodimerization activity. Predicted to contribute to transcription cis-regulatory region binding activity. Predicted to be involved in several processes, including cardiac chamber morphogenesis; in utero embryonic development; and regulation of transcription, DNA-templated. Predicted to act upstream of or within several processes, including animal organ morphogenesis; mesoderm formation; and regulation of transcription, DNA-templated. Located in nucleus. Orthologous to human HAND1 (heart and neural crest derivatives expressed 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Hand1
M08769_2.00
Mus musculus
WGABRNWDNSCAGRNNH

DNNYCTGSNHWNYVTCW
Misc
Kulakovskiy et al.(2013)
HAND1_MOUSE.H11MO.0.C
0.914 1.000
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSRNOP00000003486 bHLH 95 147

Links

Other bHLH family TFs
Other Rattus norvegicus TFs

Invalid Input OrderBy

54 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action