CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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Mnt
(
Rattus norvegicus
)
bHLH
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00010 (HLH)
IPR001092
ENSRNOG00000002894
T037167_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including cell aging; negative regulation of apoptotic signaling pathway; and regulation of transcription, DNA-templated. Predicted to be located in nucleoplasm. Orthologous to human MNT (MAX network transcriptional repressor). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
No direct experiments
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
Mnt
M01716_2.00
Mus musculus
NCACGTGNN
NNCACGTGN
PBM
Weirauch et al.(2014)
pTH4588
0.914
1.000
MNT
M02774_2.00
Homo sapiens
NVCACGTGNH
DNCACGTGBN
SELEX
Jolma et al.(2013)
MNT_1
0.914
1.000
For this family, TFs with SR scores >
0.838
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSRNOP00000003933
bHLH
223
274
TREVHNKLEKNRRAHLKECFETLKRNIPNVDDKKTSNLSVLRTALRYIQSLK
Links
Other
bHLH
family TFs
Other
Rattus norvegicus
TFs
67 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy