Ahr (Rattus norvegicus)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSRNOG00000004342 T037174_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables nuclear receptor activity and toxic substance binding activity. Involved in several processes, including cellular response to organic cyclic compound; negative regulation of alkaline phosphatase activity; and regulation of cellular macromolecule biosynthetic process. Located in cytosol and nucleus. Human ortholog(s) of this gene implicated in retinitis pigmentosa 85. Orthologous to human AHR (aryl hydrocarbon receptor). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
AHR
M08716_2.00
Homo sapiens
DCACGCNMH

DKNGCGTGH
Misc
Kulakovskiy et al.(2013)
AHR_HUMAN.H11MO.0.B
0.914 0.978
Ahr
M08747_2.00
Mus musculus
DCACGCNMH

DKNGCGTGH
Misc
Kulakovskiy et al.(2013)
AHR_MOUSE.H11MO.0.B
0.914 0.978
AHR
M09816_2.00
Homo sapiens
WSTCACGCDASYYBGRRS

SYYCVRRSTHGCGTGASW
Transfac
Matys et al.(2006)
V$AHR_01
0.914 0.978
AHR
M09817_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$AHR_Q5
0.914 0.978
AHR
M09818_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$AHR_Q6_01
0.914 0.978
AHR
M09819_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$AHR_Q6
0.914 0.978
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSRNOP00000006618 bHLH 34 79

Links

Other bHLH family TFs
Other Rattus norvegicus TFs

Invalid Input OrderBy

56 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action