Mesp2 (Rattus norvegicus)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSRNOG00000014925 T037210_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including mesoderm formation; regulation of transcription by RNA polymerase II; and somite rostral/caudal axis specification. Predicted to act upstream of or within several processes, including mesodermal cell migration; regulation of gene expression; and somitogenesis. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in spondylocostal dysostosis. Orthologous to human MESP2 (mesoderm posterior bHLH transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
MESP1
M02794_2.00
Homo sapiens
HVCACCTGBN

NVCAGGTGBD
SELEX
Jolma et al.(2013)
MESP1_1
0.914 0.982
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSRNOP00000020047 bHLH 82 136

Links

Other bHLH family TFs
Other Rattus norvegicus TFs

Invalid Input OrderBy

41 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action