CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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Sohlh2
(
Rattus norvegicus
)
bHLH
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00010 (HLH)
IPR001092
ENSRNOG00000038091
T037247_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein dimerization activity. Predicted to be involved in cell differentiation; positive regulation of transcription by RNA polymerase II; and spermatogenesis. Predicted to act upstream of or within oocyte differentiation; primary ovarian follicle growth; and regulation of gene expression. Predicted to be active in nucleus. Orthologous to several human genes including CCDC169-SOHLH2 (CCDC169-SOHLH2 readthrough). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
Sohlh2
M09890_2.00
Rattus norvegicus
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TEB1_01
(Direct)
(Direct)
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
Sohlh2
M01733_2.00
Mus musculus
NNHNCGTGVN
NBCACGNDNN
PBM
Weirauch et al.(2014)
pTH5058
0.894
0.959
SOHLH2
M01113_2.00
Homo sapiens
BCACGDRNN
NNYHCGTGV
PBM
Lambert et al.(2019)
pTH11270
0.849
0.878
SOHLH2
M04096_2.00
Homo sapiens
NBCACGTGCN
NGCACGTGVN
SELEX
Yin et al.(2017)
SOHLH2_eDBD_HT-SELEX
0.849
0.878
SOHLH2
M04097_2.00
Homo sapiens
NNMACGWDNN
NNHWCGTKNN
SELEX
Yin et al.(2017)
SOHLH2_eDBD_Methyl-HT-SELEX
0.849
0.878
For this family, TFs with SR scores >
0.838
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSRNOP00000049772
bHLH
204
252
LHSSKEKLRRERIKFCCEQLRTLLPYVKGRKSDVASVIEATVDYVKQVR
Links
Other
bHLH
family TFs
Other
Rattus norvegicus
TFs
31 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy