HLH54F (Drosophila melanogaster)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 FBgn0022740 T038422_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables protein heterodimerization activity. Involved in positive regulation of transcription by RNA polymerase II and visceral muscle development. Predicted to be located in nucleus. Is expressed in several structures, including embryonic/larval hypodermal muscle cell; extended germ band embryo; mesoderm anlage; ring gland; and visceral muscle primordium. Orthologous to several human genes including MSC (musculin). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
HLH54F
M05971_2.00		 Drosophila melanogaster
MMCACCTGYYV
BRRCAGGTGKK		 B1H
Zhu et al.(2011)
HLH54F_da_SANGER_5_FBgn0022740		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
FBpp0088516 bHLH 32 83

Links

Other bHLH family TFs
Other Drosophila melanogaster TFs

Invalid Input OrderBy

14 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action