Hand (Drosophila melanogaster)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 FBgn0032209 T038440_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in several processes, including animal organ development; dendrite morphogenesis; and positive regulation of transcription elongation from RNA polymerase II promoter. Located in nucleus. Is expressed in several structures, including cardial cell; circulatory system; dorsal closure embryo; presumptive embryonic/larval system; and trunk mesoderm. Orthologous to several human genes including HAND2 (heart and neural crest derivatives expressed 2). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Hand
M05984_2.00		 Drosophila melanogaster
CASATGGCS
SGCCATSTG		 B1H
Zhu et al.(2011)
Hand_da_SANGER_5_FBgn0032209		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
FBpp0079662 bHLH 59 111

Links

Other bHLH family TFs
Other Drosophila melanogaster TFs

Invalid Input OrderBy

26 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action