CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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Side
(
Drosophila melanogaster
)
bHLH
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00010 (HLH)
IPR001092
FBgn0032741
T038442_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anterior/posterior pattern specification; regulation of neurogenesis; and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in embryonic brain; embryonic/larval nervous system; extended germ band embryo; eye; and spermatozoon. Orthologous to human HES2 (hes family bHLH transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
Side
M03619_2.00
Drosophila melanogaster
HGRCACGTGYCD
HGRCACGTGYCD
SELEX
Nitta et al.(2015)
Side_1
(Direct)
(Direct)
Side
M05988_2.00
Drosophila melanogaster
DAAMCABCTGY
RCAGVTGKTTH
B1H
Zhu et al.(2011)
Side_SANGER_5_FBgn0032741
(Direct)
(Direct)
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
For this family, TFs with SR scores >
0.838
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
FBpp0080685
bHLH
51
115
KRTNKPLMEKRRRARINQSLAILKALILESTKTQNAKNGEGQAKHTKLEKADILELTVRHFQRHR
Links
Other
bHLH
family TFs
Other
Drosophila melanogaster
TFs
33 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy