TF Information

Fer3 *(Drosophila melanogaster)* bHLH
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF00010 (HLH)	IPR001092	FBgn0037937	T038446_2.00	Ensembl (2018-Dec-8)	Link out
NCBI Gene Info: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in developmental process; negative regulation of transcription, DNA-templated; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in embryonic brain; embryonic procephalic segment; larval ventral nerve cord; presumptive embryonic/larval central nervous system; and ventral nerve cord primordium. Orthologous to human FERD3L (Fer3 like bHLH transcription factor). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
Fer3 M05993_2.00	Drosophila melanogaster	GKVACAGVTG	CABCTGTBMC	B1H Zhu et al.(2011) Fer3_da_SANGER_5_FBgn0037937	(Direct)	(Direct)
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
FERD3L M04140_2.00	Homo sapiens	GYVACAGCTGKYRC	GYRMCAGCTGTBRC	SELEX Yin et al.(2017) FERD3L_FL_HT-SELEX_1	0.890	0.885
FERD3L M04141_2.00	Homo sapiens	GTRMCAKMTGKYRC	GYRMCAKMTGKYAC	SELEX Yin et al.(2017) FERD3L_FL_HT-SELEX_2	0.890	0.885
FERD3L M04142_2.00	Homo sapiens	GTVACAGCTGKYRC	GYRMCAGCTGTBAC	SELEX Yin et al.(2017) FERD3L_FL_Methyl-HT-SELEX_1	0.890	0.885
FERD3L M04143_2.00	Homo sapiens	GTRMCAKMTGKYRC	GYRMCAKMTGKYAC	SELEX Yin et al.(2017) FERD3L_FL_Methyl-HT-SELEX_2	0.890	0.885
For this family, TFs with SR scores > 0.838* will likely have a similar motif*