dys (Drosophila melanogaster)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 FBgn0039411 T038448_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables protein heterodimerization activity. Contributes to DNA-binding transcription factor activity and sequence-specific DNA binding activity. Involved in imaginal disc-derived leg joint morphogenesis; open tracheal system development; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Part of protein-containing complex. Is expressed in several structures, including atrium; embryonic/larval trachea; extended germ band embryo; presumptive embryonic/larval system; and tracheal fusion cell. Orthologous to human NPAS4 (neuronal PAS domain protein 4). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
dys
M05995_2.00		 Drosophila melanogaster
RDDTCGTGAYY
RRTCACGAHHY		 B1H
Zhu et al.(2011)
dys_tgo_SANGER_5_FBgn0039411		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
FBpp0112205 bHLH 119 169
FBpp0112206 bHLH 155 205
FBpp0289845 bHLH 155 205

Links

Other bHLH family TFs
Other Drosophila melanogaster TFs

Invalid Input OrderBy

39 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action