bigmax (Drosophila melanogaster)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 FBgn0039509 T038449_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in adult feeding behavior; positive regulation of transcription by RNA polymerase II; and response to glucose. Predicted to be active in nucleus. Is expressed in organism. Orthologous to human MLX (MAX dimerization protein MLX). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
bigmax
M03622_2.00		 Drosophila melanogaster
DRTCACGTGNHH
DDNCACGTGAYH		 SELEX
Nitta et al.(2015)
bigmax_1		 (Direct) (Direct)
bigmax
M05996_2.00		 Drosophila melanogaster
DTCACGTG
CACGTGAH		 B1H
Zhu et al.(2011)
Mio_bigmax_SANGER_5_FBgn0039509		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
FBpp0084543 bHLH 72 128

Links

Other bHLH family TFs
Other Drosophila melanogaster TFs

Invalid Input OrderBy

11 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action