HelroG94416 (Helobdella robusta)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 HelroG94416 T040400_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
HLH4C
M03609_2.00
Drosophila melanogaster
DDNCRCAGCTGYGNHH

DDNCRCAGCTGYGNHH
SELEX
Nitta et al.(2015)
HLH4C_1
0.887 0.865
HLH4C
M03610_2.00
Drosophila melanogaster
DRSMYCAGCTGVKSYH

DRSMBCAGCTGRKSYH
SELEX
Nitta et al.(2015)
HLH4C_2
0.887 0.865
HLH4C
M03611_2.00
Drosophila melanogaster
NRBMYCAGCTGYGNHH

DDNCRCAGCTGRKVYN
SELEX
Nitta et al.(2015)
HLH4C_3
0.887 0.865
HLH4C
M05963_2.00
Drosophila melanogaster
CACCTGMDCC

GGHKCAGGTG
B1H
Zhu et al.(2011)
HLH4C_da_SANGER_5_3_FBgn0011277
0.887 0.865
HLH4C
M05964_2.00
Drosophila melanogaster
MCAYCTGMGMMM

KKKCKCAGRTGK
B1H
Zhu et al.(2011)
HLH4C_da_SANGER_5_4_FBgn0011277
0.887 0.865
HLH4C
M05965_2.00
Drosophila melanogaster
VNHHVCACCTGMBNC

GNVKCAGGTGBDDNB
B1H
Zhu et al.(2011)
HLH4C_da_SANGER_5_FBgn0011277
0.887 0.865
HLH4C
M05966_2.00
Drosophila melanogaster
RGSMYCAGCTGCGYY

RRCGCAGCTGRKSCY
B1H
Zhu et al.(2011)
HLH4C_SANGER_5_FBgn0011277
0.887 0.865
Nhlh2
M00756_2.00
Mus musculus
NKCAGCTGHN

NDCAGCTGMN
PBM
Weirauch et al.(2013)
pTH3037
0.870 0.904
NHLH1
M02796_2.00
Homo sapiens
CGCAGCTGCB

VGCAGCTGCG
SELEX
Jolma et al.(2013)
NHLH1_1
0.870 0.904
NHLH1
M02797_2.00
Homo sapiens
VGCAGCTGCK

MGCAGCTGCB
SELEX
Jolma et al.(2013)
NHLH1_2
0.870 0.904
NHLH1
M04162_2.00
Homo sapiens
NDGNMKCAGCTGCGYCMH

DKGRCGCAGCTGMKNCHN
SELEX
Yin et al.(2017)
NHLH1_eDBD_HT-SELEX
0.870 0.904
NHLH1
M04164_2.00
Homo sapiens
NDGNMKCAGCTGCGYCMH

DKGRCGCAGCTGMKNCHN
SELEX
Yin et al.(2017)
NHLH1_FL_HT-SELEX
0.870 0.904
NHLH2
M04177_2.00
Homo sapiens
DDGNMGCAGCTGCGYCMH

DKGRCGCAGCTGCKNCHH
SELEX
Yin et al.(2017)
NHLH2_FL_HT-SELEX
0.870 0.904
Nhlh1
M08773_2.00
Mus musculus
BKGGNMNCAGCTGCGBCCYY

RRGGVCGCAGCTGNKNCCMV
Misc
Kulakovskiy et al.(2013)
HEN1_MOUSE.H11MO.0.C
0.870 0.904
NHLH1
M09875_2.00
Homo sapiens
NNDGGNMVCAGCTGVGNCCNNN

NNNGGNCBCAGCTGBKNCCHNN
Transfac
Matys et al.(2006)
V$HEN1_01
0.870 0.904
NHLH1
M09876_2.00
Homo sapiens
NDRGGVMGCAGCTGMKNCCHHN

NDDGGNMKCAGCTGCKBCCYHN
Transfac
Matys et al.(2006)
V$HEN1_02
0.870 0.904
NHLH2
M09878_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$HEN2_Q2
0.870 0.904
NHLH1
M04163_2.00
Homo sapiens
NRGBMKCAGCTGCGYCCH

DGGRCGCAGCTGMKVCYN
SELEX
Yin et al.(2017)
NHLH1_eDBD_Methyl-HT-SELEX
0.870 0.904
NHLH1
M04165_2.00
Homo sapiens
DGGNMBCAGCTGCGYCCH

DGGRCGCAGCTGVKNCCH
SELEX
Yin et al.(2017)
NHLH1_FL_Methyl-HT-SELEX
0.870 0.904
NHLH2
M04178_2.00
Homo sapiens
DGGNMBCAGCTGCGYCCH

DGGRCGCAGCTGVKNCCH
SELEX
Yin et al.(2017)
NHLH2_FL_Methyl-HT-SELEX
0.870 0.904
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
HelroP94416 bHLH 153 205

Links

Other bHLH family TFs
Other Helobdella robusta TFs

167 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
Nhlh2 Mus musculus ENSMUSG00000048540 D 0.870
HLH4C Drosophila melanogaster FBgn0011277 D 0.887
Nhlh1 Mus musculus ENSMUSG00000051251 D 0.870
NHLH2 Homo sapiens ENSG00000177551 D 0.870
NHLH1 Homo sapiens ENSG00000171786 D 0.870
TC007725 Tribolium castaneum TC007725 I 0.890
SPU_009231 Strongylocentrotus purpuratus SPU_009231 I 0.890
SMAR007908 Strigamia maritima SMAR007908 I 0.890
RPRC001173 Rhodnius prolixus RPRC001173 I 0.890
PHUM229200 Pediculus humanus PHUM229200 I 0.890
NV10733 Nasonia vitripennis NV10733 I 0.870
Cmyd_10010324 Chelonia mydas Cmyd_10010324 I 0.870
YQE_00442 Dendroctonus ponderosae YQE_00442 I 0.890
Cmyd_10001044 Chelonia mydas Cmyd_10001044 I 0.858
Cflo_11933--XP_001122281.1_APIME Camponotus floridanus Cflo_11933--XP_001122281.1_APIME I 0.870
Alligator_sinensis_CCG018876.1 Alligator sinensis Alligator_sinensis_CCG018876.1 I 0.870
Alligator_sinensis_CCG011163.1 Alligator sinensis Alligator_sinensis_CCG011163.1 I 0.870
Aan_R014318 Calypte anna Aan_R014318 I 0.870
YQE_11502 Dendroctonus ponderosae YQE_11502 I 0.890
YQE_04623 Dendroctonus ponderosae YQE_04623 I 0.890
HHAL001761-PA Halyomorpha halys HHAL001761-PA I 0.890
MESCA010279 Megaselia scalaris MESCA010279 I 0.867
MCINX015834 Melitaea cinxia MCINX015834 I 0.870
LotgiG133561 Lottia gigantea LotgiG133561 I 0.890
GD16284 Drosophila simulans FBgn0187911 I 0.887
GM12676 Drosophila sechellia FBgn0167612 I 0.887
GL14555 Drosophila persimilis FBgn0152160 I 0.887
GI16068 Drosophila mojavensis FBgn0138817 I 0.887
GH17630 Drosophila grimshawi FBgn0125100 I 0.887
GG18528 Drosophila erecta FBgn0110741 I 0.887
GF20856 Drosophila ananassae FBgn0097862 I 0.887
GA15893 Drosophila pseudoobscura FBgn0075909 I 0.887
GJ15714 Drosophila virilis FBgn0202902 I 0.887
GK16457 Drosophila willistoni FBgn0218459 I 0.887
GE16844 Drosophila yakuba FBgn0234336 I 0.887
L798_00559 Zootermopsis nevadensis L798_00559 I 0.890
KGM_06532 Danaus plexippus KGM_06532 I 0.870
ISCW014797 Ixodes scapularis ISCW014797 I 0.890
HMEL010237 Heliconius melpomene HMEL010237 I 0.838
HelroG153470 Helobdella robusta HelroG153470 I 0.870
HelroG138545 Helobdella robusta HelroG138545 I 0.870
GB53325 Apis mellifera GB53325 I 0.870
GB49291 Apis mellifera GB49291 I 0.870
ENSXMAG00000020348 Xiphophorus maculatus ENSXMAG00000020348 I 0.890
nRc.2.0.1.g35713 Romanomermis culicivorax nRc.2.0.1.g35713 I 0.870
AMEM004741 Anopheles merus AMEM004741 I 0.890
AMEC009920 Anopheles melas AMEC009920 I 0.890
AMAM022568 Anopheles maculatus AMAM022568 I 0.890
AFUN005050 Anopheles funestus AFUN005050 I 0.890
AFAF009162 Anopheles farauti AFAF009162 I 0.890
AEPI011485 Anopheles epiroticus AEPI011485 I 0.890
ADIR001683 Anopheles dirus ADIR001683 I 0.890
ACUA026679 Anopheles culicifacies ACUA026679 I 0.890
AMIN011405 Anopheles minimus AMIN011405 I 0.890
AQUA014034 Anopheles quadriannulatus AQUA014034 I 0.890
BXY_0231500 Bursaphelenchus xylophilus BXY_0231500 I 0.840
PPAI007861 Phlebotomus papatasi PPAI007861 I 0.890
MDOA013398 Musca domestica MDOA013398 I 0.887
MDOA007431 Musca domestica MDOA007431 I 0.887
LLOJ002704 Lutzomyia longipalpis LLOJ002704 I 0.890
BGLB013717 Biomphalaria glabrata BGLB013717 I 0.890
ASTEI10641 Anopheles stephensi ASTEI10641 I 0.890
ASIS019843 Anopheles sinensis ASIS019843 I 0.890
ACUA009159 Anopheles culicifacies ACUA009159 I 0.890
ACOM036372 Anopheles coluzzii ACOM036372 I 0.890
AATE010880 Anopheles atroparvus AATE010880 I 0.890
Ocbimv22001940m.g Octopus bimaculoides Ocbimv22001940m.g I 0.890
Pvit_07565 Pogona vitticeps Pvit_07565 I 0.870
Ogr08231 Ophisaurus gracilis Ogr08231 I 0.870
Hsal_11874--XP_001122281.1_APIME Harpegnathos saltator Hsal_11874--XP_001122281.1_APIME I 0.870
Gfo_R014815 Geospiza fortis Gfo_R014815 I 0.890
ENSP00000405915 Macaca fascicularis ENSP00000405915 I 0.870
ENSP00000358519-D1 Bos grunniens ENSP00000358519-D1 I 0.870
ENSP00000302189 Macaca fascicularis ENSP00000302189 I 0.870
Sakowv30004475m.g Saccoglossus kowalevskii Sakowv30004475m.g I 0.890
CLEC002464 Cimex lectularius CLEC002464 I 0.890
AARA003512 Anopheles arabiensis AARA003512 I 0.890
AALB004585 Anopheles albimanus AALB004585 I 0.890
nhlh1.L Xenopus laevis XB-GENE-989792 I 0.870
nhlh1 Xenopus tropicalis XB-GENE-989790 I 0.870
nhlh1.S Xenopus laevis XB-GENE-6252028 I 0.870
SMU15030866 Schmidtea mediterranea SMU15030866 I 0.857
LDEC000946 Leptinotarsa decemlineata LDEC000946 I 0.890
LCUP012274 Lucilia cuprina LCUP012274 I 0.887
Cmyd_10014342 Chelonia mydas Cmyd_10014342 I 0.870
NHLH2 Tursiops truncatus ENSTTRG00000003112 I 0.870
AAEL004428 Aedes aegypti AAEL004428 I 0.890
ENSFALG00000006103 Ficedula albicollis ENSFALG00000006103 I 0.870
NHLH1 Echinops telfairi ENSETEG00000009677 I 0.870
NHLH1 Equus caballus ENSECAG00000004612 I 0.870
NHLH1 Dasypus novemcinctus ENSDNOG00000038600 I 0.870
NHLH2 Dasypus novemcinctus ENSDNOG00000008961 I 0.870
nhlh2 Danio rerio ENSDARG00000025495 I 0.890
ENSCSAG00000000172 Chlorocebus sabaeus ENSCSAG00000000172 I 0.870
ENSCSAG00000000087 Chlorocebus sabaeus ENSCSAG00000000087 I 0.870
ENSFCAG00000028313 Felis catus ENSFCAG00000028313 I 0.870
nhlh2 Gasterosteus aculeatus ENSGACG00000014053 I 0.890
ENSLOCG00000017787 Lepisosteus oculatus ENSLOCG00000017787 I 0.890
NHLH1 Loxodonta africana ENSLAFG00000011163 I 0.870
NHLH2 Loxodonta africana ENSLAFG00000007456 I 0.870
ENSLACG00000011363 Latimeria chalumnae ENSLACG00000011363 I 0.870
ENSGMOG00000020309 Gadus morhua ENSGMOG00000020309 I 0.890
NHLH1 Gorilla gorilla ENSGGOG00000015736 I 0.870
NHLH2 Gorilla gorilla ENSGGOG00000008283 I 0.870
NHLH1 Gallus gallus ENSGALG00000025817 I 0.870
NHLH2 Cavia porcellus ENSCPOG00000026593 I 0.870
NHLH1 Cavia porcellus ENSCPOG00000021596 I 0.870
DAPPUDRAFT_66944 Daphnia pulex DAPPUDRAFT_66944 I 0.870
CGI_10002829 Crassostrea gigas CGI_10002829 I 0.870
CapteG162858 Capitella teleta CapteG162858 I 0.890
BGIBMGA008476 Bombyx mori BGIBMGA008476 I 0.870
AGAP004907 Anopheles gambiae AGAP004907 I 0.890
ADAC006978 Anopheles darlingi ADAC006978 I 0.890
ACYPI007008 Acyrthosiphon pisum ACYPI007008 I 0.890
ACEP10202 Atta cephalotes ACEP10202 I 0.870
NHLH2 Anolis carolinensis ENSACAG00000003304 I 0.870
ENSACAG00000010649 Anolis carolinensis ENSACAG00000010649 I 0.870
NHLH2 Callithrix jacchus ENSCJAG00000012807 I 0.870
NHLH1 Callithrix jacchus ENSCJAG00000005775 I 0.870
NHLH1 Canis familiaris ENSCAFG00000023513 I 0.870
NHLH2 Canis familiaris ENSCAFG00000009767 I 0.870
NHLH1 Bos taurus ENSBTAG00000020027 I 0.870
NHLH2 Bos taurus ENSBTAG00000015067 I 0.870
ENSAMXG00000026006 Astyanax mexicanus ENSAMXG00000026006 I 0.890
ENSAMEG00000010851 Ailuropoda melanoleuca ENSAMEG00000010851 I 0.894
ENSMEUG00000003022 Macropus eugenii ENSMEUG00000003022 I 0.870
ENSMGAG00000016096 Meleagris gallopavo ENSMGAG00000016096 I 0.870
ENSMICG00000002851 Microcebus murinus ENSMICG00000002851 I 0.870
Nhlh2 Rattus norvegicus ENSRNOG00000054375 I 0.870
Nhlh1 Rattus norvegicus ENSRNOG00000005166 I 0.870
NHLH2 Pteropus vampyrus ENSPVAG00000012688 I 0.870
NHLH1 Pteropus vampyrus ENSPVAG00000007987 I 0.870
NHLH1 Pan troglodytes ENSPTRG00000001551 I 0.870
NHLH2 Pan troglodytes ENSPTRG00000001149 I 0.870
ENSPPYG00000000988 Pongo abelii ENSPPYG00000000988 I 0.870
ENSPPYG00000000632 Pongo abelii ENSPPYG00000000632 I 0.870
ENSSHAG00000006613 Sarcophilus harrisii ENSSHAG00000006613 I 0.870
ENSSHAG00000015472 Sarcophilus harrisii ENSSHAG00000015472 I 0.870
ENSTSYG00000000582 Tarsius syrichta ENSTSYG00000000582 I 0.870
nhlh2 Takifugu rubripes ENSTRUG00000003636 I 0.890
nhlh2 Tetraodon nigroviridis ENSTNIG00000010331 I 0.890
NHLH1 Taeniopygia guttata ENSTGUG00000013389 I 0.870
ENSSTOG00000027988 Ictidomys tridecemlineatus ENSSTOG00000027988 I 0.870
ENSSTOG00000019698 Ictidomys tridecemlineatus ENSSTOG00000019698 I 0.870
NHLH2 Sus scrofa ENSSSCG00000006744 I 0.870
NHLH1 Sus scrofa ENSSSCG00000006384 I 0.870
ENSPFOG00000020651 Poecilia formosa ENSPFOG00000020651 I 0.890
NHLH1 Procavia capensis ENSPCAG00000009061 I 0.870
ENSMPUG00000019473 Mustela putorius furo ENSMPUG00000019473 I 0.870
ENSMPUG00000019387 Mustela putorius furo ENSMPUG00000019387 I 0.870
NHLH1 Monodelphis domestica ENSMODG00000024591 I 0.870
NHLH2 Monodelphis domestica ENSMODG00000023228 I 0.870
NHLH1 Macaca mulatta ENSMMUG00000021865 I 0.870
ENSMMUG00000008971 Macaca mulatta ENSMMUG00000008971 I 0.870
NHLH2 Myotis lucifugus ENSMLUG00000015989 I 0.870
NHLH1 Microcebus murinus ENSMICG00000012700 I 0.870
ENSNLEG00000013637 Nomascus leucogenys ENSNLEG00000013637 I 0.870
NHLH2 Ornithorhynchus anatinus ENSOANG00000009820 I 0.870
ENSPANG00000011970 Papio anubis ENSPANG00000011970 I 0.870
ENSPANG00000001481 Papio anubis ENSPANG00000001481 I 0.870
NHLH2 Ochotona princeps ENSOPRG00000006661 I 0.870
ENSONIG00000021015 Oreochromis niloticus ENSONIG00000021015 I 0.890
ENSONIG00000020673 Oreochromis niloticus ENSONIG00000020673 I 0.846
NHLH2 Otolemur garnettii ENSOGAG00000034540 I 0.870
NHLH1 Otolemur garnettii ENSOGAG00000010592 I 0.870
NHLH2 Oryctolagus cuniculus ENSOCUG00000015744 I 0.870
NHLH1 Tursiops truncatus ENSTTRG00000001840 I 0.870