| NCBI Gene Info:Enables DNA binding activity; DNA-binding transcription factor activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Contributes to sequence-specific DNA binding activity. Involved in several processes, including cell fate specification; positive regulation of transcription by RNA polymerase II; and social behavior. Located in nucleus. Part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including anal region; epithelial system; gonadal primordium; nervous system; and vulva. Human ortholog(s) of this gene implicated in renal cell carcinoma. Orthologous to human ARNT (aryl hydrocarbon receptor nuclear translocator) and ARNT2 (aryl hydrocarbon receptor nuclear translocator 2). [provided by Alliance of Genome Resources, Apr 2022] |