lin-32 (Caenorhabditis elegans)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 WBGene00003018 T046294_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables protein heterodimerization activity; protein homodimerization activity; and sequence-specific DNA binding activity. Involved in several processes, including aging; nematode male tail tip morphogenesis; and neurogenesis. Located in nucleus. Is expressed in several structures, including QL; QL.a; QR; oxygen sensory neurons; and ray precursor cell. Human ortholog(s) of this gene implicated in persistent hyperplastic primary vitreous. Orthologous to several human genes including ATOH1 (atonal bHLH transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
T14F9.5 bHLH 73 125

Links

Other bHLH family TFs
Other Caenorhabditis elegans TFs

4 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
CRE00941 Caenorhabditis remanei CRE00941 N 0.890
CJA03891 Caenorhabditis japonica CJA03891 N 0.890
CBN14646 Caenorhabditis brenneri CBN14646 N 0.890
CBG14057 Caenorhabditis briggsae CBG14057 N 0.890