CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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TYE7
(
Saccharomyces cerevisiae
)
bHLH
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00010 (HLH)
IPR001092
YOR344C
T046371_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Enables DNA-binding transcription factor activity. Involved in positive regulation of glycolytic process and transcription elongation from RNA polymerase II promoter. Located in chromatin. Human ortholog(s) of this gene implicated in cardiovascular system disease; disease of metabolism; and type 2 diabetes mellitus. Orthologous to human SREBF1 (sterol regulatory element binding transcription factor 1) and USF1 (upstream transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
TYE7
M00011_2.00
Saccharomyces cerevisiae
VTCACGTG
CACGTGAB
PBM
Badis et al.(2008)
TYE7_2097
(Direct)
(Direct)
TYE7
M01521_2.00
Saccharomyces cerevisiae
NRYCASSTGD
HCASSTGRYN
PBM
Zhu et al.(2009)
Tye7
(Direct)
(Direct)
TYE7
M07441_2.00
Saccharomyces cerevisiae
TCACGTG
CACGTGA
PBM, CSA and or DIP-chip
Mathelier et al.(2014)
MA0409.1
(Direct)
(Direct)
TYE7
M08489_2.00
Saccharomyces cerevisiae
RTCACGTGA
TCACGTGAY
Misc
DeBoer et al.(2011)
YOR344C_397
(Direct)
(Direct)
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
For this family, TFs with SR scores >
0.838
will likely have a similar motif
Experimental Constructs
Motif ID
Domain
From
To
Sequence
M00011_2.00
bHLH
51
136
QKQAHNKIEKRYRININTKIARLQQIIPWVASEQTAFEVGDSVKKQDEDGAETAATTPLPSAAATSTKLNKSMILEKAVDYILYLQ
M01521_2.00
bHLH
181
266
QKQAHNKIEKRYRININTKIARLQQIIPWVASEQTAFEVGDSVKKQDEDGAETAATTPLPSAAATSTKLNKSMILEKAVDYILYLQ
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
YOR344C
bHLH
181
266
QKQAHNKIEKRYRININTKIARLQQIIPWVASEQTAFEVGDSVKKQDEDGAETAATTPLPSAAATSTKLNKSMILEKAVDYILYLQ
Links
Other
bHLH
family TFs
Other
Saccharomyces cerevisiae
TFs
15 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy