ENSP00000256495-D1 (Bos grunniens)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00010 (HLH) IPR001092 ENSP00000256495-D1 T047196_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
This gene encodes a basic helix-loop-helix protein expressed in various tissues. The encoded protein can interact with ARNTL or compete for E-box binding sites in the promoter of PER1 and repress CLOCK/ARNTL's transactivation of PER1. This gene is believed to be involved in the control of circadian rhythm and cell differentiation. [provided by RefSeq, Feb 2014]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Bhlhe40
M00119_2.00
Mus musculus
DCACGTGMN

NKCACGTGH
PBM
Badis et al.(2009)
Bhlhb2_1274
0.914 1.000
Bhlhe40
M01738_2.00
Mus musculus
NCACRNBN

NVNYGTGN
PBM
Weirauch et al.(2014)
pTH4330
0.914 1.000
BHLHE40
M02788_2.00
Homo sapiens
NKCACGTGMH

DKCACGTGMN
SELEX
Jolma et al.(2013)
BHLHB2_1
0.914 1.000
Bhlhe40
M02817_2.00
Mus musculus
NKCACGTGMN

NKCACGTGMN
SELEX
Jolma et al.(2013)
Bhlhb2_1
0.914 1.000
Bhlhe40
M02818_2.00
Mus musculus
NKCACGTGMN

NKCACGTGMN
SELEX
Jolma et al.(2013)
Bhlhb2_2
0.914 1.000
BHLHE40
M04126_2.00
Homo sapiens
VTCACGTGAB

VTCACGTGAB
SELEX
Yin et al.(2017)
BHLHE40_eDBD_HT-SELEX
0.914 1.000
BHLHE40
M07798_2.00
Homo sapiens
DCACGTGMSN

NSKCACGTGH
ChIP-seq
Gerstein et al.(2012)
HepG2_BHLHE40_HudsonAlpha
0.914 1.000
BHLHE40
M08726_2.00
Homo sapiens
DDCACGTGMS

SKCACGTGHH
Misc
Kulakovskiy et al.(2013)
BHE40_HUMAN.H11MO.0.A
0.914 1.000
Bhlhe40
M08761_2.00
Mus musculus
DCACGTGMS

SKCACGTGH
Misc
Kulakovskiy et al.(2013)
BHE40_MOUSE.H11MO.0.A
0.914 1.000
BHLHE40
M09456_2.00
Homo sapiens
DCACGTGMNN

NNKCACGTGH
Misc
Heinz et al.(2010)
HepG2-BHLHE40_GSE31477
0.914 1.000
BHLHE40
M09842_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$BHLHE40_03
0.914 1.000
BHLHE40
M09843_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$DEC1_Q2
0.914 1.000
BHLHE40
M09844_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$DEC1_Q3
0.914 1.000
BHLHE40
M09845_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$STRA13_01
0.914 1.000
BHLHE40
M04127_2.00
Homo sapiens
RTCACGTGAY

RTCACGTGAY
SELEX
Yin et al.(2017)
BHLHE40_eDBD_Methyl-HT-SELEX
0.914 1.000
Bhlhe41
M01739_2.00
Mus musculus
NMNCGTGMN

NKCACGNKN
PBM
Weirauch et al.(2014)
pTH5060
0.914 0.981
BHLHE41
M02782_2.00
Homo sapiens
NKCACGTGMN

NKCACGTGMN
SELEX
Jolma et al.(2013)
BHLHB3_1
0.914 0.981
BHLHE41
M02783_2.00
Homo sapiens
RKCACGTGAY

RTCACGTGMY
SELEX
Jolma et al.(2013)
BHLHE41_1
0.914 0.981
BHLHE41
M04106_2.00
Homo sapiens
VTCACGTGAB

VTCACGTGAB
SELEX
Yin et al.(2017)
BHLHE41_eDBD_HT-SELEX
0.914 0.981
BHLHE41
M09833_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$DEC2_Q2
0.914 0.981
BHLHE41
M09834_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$DEC2_Q3
0.914 0.981
BHLHE41
M04107_2.00
Homo sapiens
RTCACGTGAY

RTCACGTGAY
SELEX
Yin et al.(2017)
BHLHE41_eDBD_Methyl-HT-SELEX
0.914 0.981
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000256495-D1 bHLH 54 108

Links

Other bHLH family TFs
Other Bos grunniens TFs

117 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ENSPPYG00000004372 Pongo abelii ENSPPYG00000004372 I 0.914
ENSPPYG00000013696 Pongo abelii ENSPPYG00000013696 I 0.914
ENSPFOG00000007800 Poecilia formosa ENSPFOG00000007800 I 0.914
ENSPANG00000008563 Papio anubis ENSPANG00000008563 I 0.914
ENSPANG00000006688 Papio anubis ENSPANG00000006688 I 0.914
ENSPSIG00000016504 Pelodiscus sinensis ENSPSIG00000016504 I 0.914
ENSPSIG00000018157 Pelodiscus sinensis ENSPSIG00000018157 I 0.914
BHLHE40 Pteropus vampyrus ENSPVAG00000007723 I 0.914
BHLHE41 Pteropus vampyrus ENSPVAG00000004507 I 0.914
BHLHE40 Pan troglodytes ENSPTRG00000014571 I 0.914
BHLHE41 Pan troglodytes ENSPTRG00000004779 I 0.914
dec1b Oryzias latipes ENSORLG00000014397 I 0.914
ENSOPRG00000009637 Ochotona princeps ENSOPRG00000009637 I 0.914
BHLHE40 Ornithorhynchus anatinus ENSOANG00000003764 I 0.914
ENSNLEG00000005307 Nomascus leucogenys ENSNLEG00000005307 I 0.914
ENSNLEG00000003704 Nomascus leucogenys ENSNLEG00000003704 I 0.914
Bhlhe41 Mus musculus ENSMUSG00000030256 D 0.914
ENSOARG00000007840 Ovis aries ENSOARG00000007840 I 0.914
ENSOARG00000019968 Ovis aries ENSOARG00000019968 I 0.914
ENSONIG00000019148 Oreochromis niloticus ENSONIG00000019148 I 0.914
ENSOGAG00000032001 Otolemur garnettii ENSOGAG00000032001 I 0.914
BHLHE40 Otolemur garnettii ENSOGAG00000029762 I 0.914
BHLHE41 Anolis carolinensis ENSACAG00000000432 I 0.914
Bhlhe40 Rattus norvegicus ENSRNOG00000007152 I 0.914
Bhlhe41 Rattus norvegicus ENSRNOG00000048961 I 0.914
ENSMMUP00000024507 Macaca fascicularis ENSMMUP00000024507 I 0.914
ENSP00000256495 Macaca fascicularis ENSP00000256495 I 0.914
ENSBTAP00000040772-D1 Bos grunniens ENSBTAP00000040772-D1 I 0.914
Cmyd_10013769 Chelonia mydas Cmyd_10013769 I 0.914
Cmyd_10013122 Chelonia mydas Cmyd_10013122 I 0.914
Gfo_R015175 Geospiza fortis Gfo_R015175 I 0.914
Myotis_brandtii_BHLHE40_10019553 Myotis brandtii Myotis_brandtii_BHLHE40_10019553 I 0.914
bhlhe41 Xenopus tropicalis XB-GENE-994875 I 0.914
Pvit_19380 Pogona vitticeps Pvit_19380 I 0.914
Pvit_15832 Pogona vitticeps Pvit_15832 I 0.914
Myotis_brandtii_BHLHE41_10027341 Myotis brandtii Myotis_brandtii_BHLHE41_10027341 I 0.914
Alligator_sinensis_CCG021907.1 Alligator sinensis Alligator_sinensis_CCG021907.1 I 0.914
Aan_R007938 Calypte anna Aan_R007938 I 0.914
ENSSTOG00000021007 Ictidomys tridecemlineatus ENSSTOG00000021007 I 0.914
ENSSTOG00000000793 Ictidomys tridecemlineatus ENSSTOG00000000793 I 0.914
BHLHE41 Sus scrofa ENSSSCG00000028552 I 0.914
ENSSSCG00000011534 Sus scrofa ENSSSCG00000011534 I 0.914
ENSTGUG00000012230 Taeniopygia guttata ENSTGUG00000012230 I 0.914
BHLHE40 Takifugu rubripes ENSTRUG00000011390 I 0.914
ENSXMAG00000002248 Xiphophorus maculatus ENSXMAG00000002248 I 0.914
BHLHE41 Tursiops truncatus ENSTTRG00000014501 I 0.914
BHLHE40 Tursiops truncatus ENSTTRG00000002786 I 0.914
ENSTSYG00000002535 Tarsius syrichta ENSTSYG00000002535 I 0.914
Bhlhe40 Mus musculus ENSMUSG00000030103 D 0.914
BHLHE40 Oryctolagus cuniculus ENSOCUG00000015177 I 0.914
BHLHE40 Equus caballus ENSECAG00000015069 I 0.914
BHLHE41 Echinops telfairi ENSETEG00000017468 I 0.914
ENSECAG00000000494 Equus caballus ENSECAG00000000494 I 0.914
ENSDORG00000006908 Dipodomys ordii ENSDORG00000006908 I 0.914
BHLHE40 Dasypus novemcinctus ENSDNOG00000035717 I 0.914
ENSFALG00000003877 Ficedula albicollis ENSFALG00000003877 I 0.914
ENSFALG00000013572 Ficedula albicollis ENSFALG00000013572 I 0.914
BHLHE40 Homo sapiens ENSG00000134107 D 0.914
BHLHE40 Gasterosteus aculeatus ENSGACG00000000659 I 0.914
BHLHE41 Homo sapiens ENSG00000123095 D 0.914
ENSMPUG00000017029 Mustela putorius furo ENSMPUG00000017029 I 0.914
BHLHE40 Felis catus ENSFCAG00000002966 I 0.914
bhlhe41 Danio rerio ENSDARG00000041691 I 0.914
ENSCSAG00000010905 Chlorocebus sabaeus ENSCSAG00000010905 I 0.914
ENSAMXG00000020366 Astyanax mexicanus ENSAMXG00000020366 I 0.914
BHLHE40 Bos taurus ENSBTAG00000009863 I 0.914
ENSAMEG00000016060 Ailuropoda melanoleuca ENSAMEG00000016060 I 0.914
ENSAMEG00000011905 Ailuropoda melanoleuca ENSAMEG00000011905 I 0.914
BHLHE40 Anolis carolinensis ENSACAG00000012577 I 0.914
BHLHE41 Bos taurus ENSBTAG00000030575 I 0.914
BHLHE40 Canis familiaris ENSCAFG00000005621 I 0.914
ENSCSAG00000007728 Chlorocebus sabaeus ENSCSAG00000007728 I 0.914
ENSCPOG00000025122 Cavia porcellus ENSCPOG00000025122 I 0.914
BHLHE40 Callithrix jacchus ENSCJAG00000015832 I 0.914
ENSCAFG00000031081 Canis familiaris ENSCAFG00000031081 I 0.914
BHLHE40 Gallus gallus ENSGALG00000008308 I 0.914
ENSFCAG00000022143 Felis catus ENSFCAG00000022143 I 0.914
ENSMEUG00000013058 Macropus eugenii ENSMEUG00000013058 I 0.914
BHLHE41 Myotis lucifugus ENSMLUG00000028371 I 0.914
ENSMMUG00000014588 Macaca mulatta ENSMMUG00000014588 I 0.914
ENSMMUG00000018629 Macaca mulatta ENSMMUG00000018629 I 0.914
ENSMEUG00000010801 Macropus eugenii ENSMEUG00000010801 I 0.914
BHLHE41 Loxodonta africana ENSLAFG00000030711 I 0.914
ENSLOCG00000010962 Lepisosteus oculatus ENSLOCG00000010962 I 0.914
ENSLOCG00000015327 Lepisosteus oculatus ENSLOCG00000015327 I 0.914
BHLHE41 Gorilla gorilla ENSGGOG00000015498 I 0.914
BHLHE40 Loxodonta africana ENSLAFG00000004896 I 0.914
ENSLACG00000013163 Latimeria chalumnae ENSLACG00000013163 I 0.914
BHLHE40 Gorilla gorilla ENSGGOG00000015864 I 0.914
ENSMPUG00000010346 Mustela putorius furo ENSMPUG00000010346 I 0.914
BHLHE40 Monodelphis domestica ENSMODG00000004516 I 0.914
BHLHE41 Monodelphis domestica ENSMODG00000016551 I 0.914
ENSGMOG00000004494 Gadus morhua ENSGMOG00000004494 I 0.914
ENSNLEG00000026535 Nomascus leucogenys ENSNLEG00000026535 I 0.894
bhlhe40.L Xenopus laevis XB-GENE-865608 I 0.890
bhlhe40 Xenopus tropicalis XB-GENE-486416 I 0.890
ENSXMAG00000008981 Xiphophorus maculatus ENSXMAG00000008981 I 0.890
bhlhe40.S Xenopus laevis XB-GENE-17337587 I 0.890
ENSAMXG00000007020 Astyanax mexicanus ENSAMXG00000007020 I 0.890
ENSONIG00000020277 Oreochromis niloticus ENSONIG00000020277 I 0.890
bhlhe40 Takifugu rubripes ENSTRUG00000014524 I 0.890
dec1a Oryzias latipes ENSORLG00000012739 I 0.890
ENSPFOG00000004275 Poecilia formosa ENSPFOG00000004275 I 0.890
ENSGMOG00000002353 Gadus morhua ENSGMOG00000002353 I 0.890
bhlhe40 Gasterosteus aculeatus ENSGACG00000011940 I 0.890
bhlhe40 Tetraodon nigroviridis ENSTNIG00000007338 I 0.890
bhlhe40 Danio rerio ENSDARG00000004060 I 0.890
ENSPMAG00000003684 Petromyzon marinus ENSPMAG00000003684 I 0.889
bhlhe41 Gasterosteus aculeatus ENSGACG00000011684 I 0.889
ENSPFOG00000015542 Poecilia formosa ENSPFOG00000015542 I 0.889
bhlhe41 Tetraodon nigroviridis ENSTNIG00000012152 I 0.889
ENSONIG00000014711 Oreochromis niloticus ENSONIG00000014711 I 0.889
Afo_R006295 Aptenodytes forsteri Afo_R006295 I 0.889
ENSXMAG00000001113 Xiphophorus maculatus ENSXMAG00000001113 I 0.889
bhlhe41 Oryzias latipes ENSORLG00000011401 I 0.889
bhlhe41 Takifugu rubripes ENSTRUG00000005639 I 0.889
ENSGMOG00000003444 Gadus morhua ENSGMOG00000003444 I 0.858