ENSP00000266503 (Macaca fascicularis)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00010 (HLH) IPR001092 ENSP00000266503 T047204_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
This gene encodes a basic helix-loop-helix transcription factor belonging to the PAS (PER, ARNT, SIM) superfamily. The PAS proteins play important roles in adaptation to low atmospheric and cellular oxygen levels, exposure to certain environmental pollutants, and diurnal oscillations in light and temperature. This protein forms a transcriptionally active heterodimer with the circadian CLOCK protein, the structurally related MOP4, and hypoxia-inducible factors, such as HIF1alpha. Consistent with its role as a biologically relevant partner of circadian and hypoxia factors, this protein is coexpressed in regions of the brain such as the thalamus, hypothalamus, and amygdala. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000266503 bHLH 99 151

Links

Other bHLH family TFs
Other Macaca fascicularis TFs

49 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ENSPFOG00000016287 Poecilia formosa ENSPFOG00000016287 I 0.884
arntl2 Tetraodon nigroviridis ENSTNIG00000012142 I 0.884
ENSXMAG00000001482 Xiphophorus maculatus ENSXMAG00000001482 I 0.884
arntl2 Danio rerio ENSDARG00000041381 I 0.884
ENSONIG00000014665 Oreochromis niloticus ENSONIG00000014665 I 0.864
arntl2 Oryzias latipes ENSORLG00000010946 I 0.864
ENSAMXG00000020233 Astyanax mexicanus ENSAMXG00000020233 I 0.884
arntl2 Takifugu rubripes ENSTRUG00000007832 I 0.884
ARNTL2 Pteropus vampyrus ENSPVAG00000013771 N 0.869
ARNTL2 Sus scrofa ENSSSCG00000000551 N 0.843
ENSPSIG00000009416 Pelodiscus sinensis ENSPSIG00000009416 N 0.914
ENSTGUG00000012163 Taeniopygia guttata ENSTGUG00000012163 N 0.914
ARNTL2 Pan troglodytes ENSPTRG00000004788 N 0.914
ENSPPYG00000004380 Pongo abelii ENSPPYG00000004380 N 0.914
ENSSTOG00000001344 Ictidomys tridecemlineatus ENSSTOG00000001344 N 0.855
ENSTSYG00000005541 Tarsius syrichta ENSTSYG00000005541 N 0.914
Pvit_19389 Pogona vitticeps Pvit_19389 N 0.886
Ogr07520 Ophisaurus gracilis Ogr07520 N 0.855
Myotis_brandtii_ARNTL2_10027352 Myotis brandtii Myotis_brandtii_ARNTL2_10027352 N 0.851
Gfo_R015185 Geospiza fortis Gfo_R015185 N 0.914
ENSP00000266503-D1 Bos grunniens ENSP00000266503-D1 N 0.850
Cmyd_10013756 Chelonia mydas Cmyd_10013756 N 0.914
Brh_R011091 Buceros rhinoceros Brh_R011091 N 0.914
Afo_R006305 Aptenodytes forsteri Afo_R006305 N 0.914
Aan_R007949 Calypte anna Aan_R007949 N 0.914
ARNTL2 Tursiops truncatus ENSTTRG00000012339 N 0.914
Tal_R011603 Tyto alba Tal_R011603 N 0.914
ARNTL2 Procavia capensis ENSPCAG00000008486 N 0.914
ARNTL2 Gallus gallus ENSGALG00000014096 N 0.914
ARNTL2 Homo sapiens ENSG00000029153 N 0.914
ARNTL2 Felis catus ENSFCAG00000000386 N 0.874
ENSFALG00000003942 Ficedula albicollis ENSFALG00000003942 N 0.914
ENSCSAG00000007636 Chlorocebus sabaeus ENSCSAG00000007636 N 0.914
ARNTL2 Canis familiaris ENSCAFG00000011089 N 0.886
ARNTL2 Bos taurus ENSBTAG00000011804 N 0.850
ENSAPLG00000008758 Anas platyrhynchos ENSAPLG00000008758 N 0.914
ENSAMEG00000011610 Ailuropoda melanoleuca ENSAMEG00000011610 N 0.914
ENSLACG00000009646 Latimeria chalumnae ENSLACG00000009646 N 0.856
ENSLOCG00000015224 Lepisosteus oculatus ENSLOCG00000015224 N 0.856
ENSPANG00000004474 Papio anubis ENSPANG00000004474 N 0.914
ARNTL2 Otolemur garnettii ENSOGAG00000011668 N 0.860
ENSOARG00000019779 Ovis aries ENSOARG00000019779 N 0.871
ENSNLEG00000005463 Nomascus leucogenys ENSNLEG00000005463 N 0.914
ENSMPUG00000010512 Mustela putorius furo ENSMPUG00000010512 N 0.914
ARNTL2 Macaca mulatta ENSMMUG00000023249 N 0.914
ARNTL2 Myotis lucifugus ENSMLUG00000003256 N 0.851
ARNTL2 Meleagris gallopavo ENSMGAG00000013735 N 0.914
ENSMEUG00000007045 Macropus eugenii ENSMEUG00000007045 N 0.890
ARNTL2 Anolis carolinensis ENSACAG00000012446 N 0.886