ENSP00000320886 (Macaca fascicularis)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00010 (HLH) IPR001092 ENSP00000320886 T047229_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
MLXIPL
M02772_2.00
Homo sapiens
DNCACGTGHH

DDCACGTGNH
SELEX
Jolma et al.(2013)
MLXIPL_1
0.914 1.000
MLXIPL
M09788_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CHREBP_Q6
0.914 1.000
MLXIPL
M09789_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CHREB_Q6_01
0.914 1.000
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000320886 bHLH 636 690

Links

Other bHLH family TFs
Other Macaca fascicularis TFs

41 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ENSPPYG00000017501 Pongo abelii ENSPPYG00000017501 I 0.914
ENSPSIG00000015212 Pelodiscus sinensis ENSPSIG00000015212 I 0.914
MLXIPL Pan troglodytes ENSPTRG00000019274 I 0.914
MLXIPL Procavia capensis ENSPCAG00000010393 I 0.914
ENSPANG00000008676 Papio anubis ENSPANG00000008676 I 0.914
Mlxipl Mus musculus ENSMUSG00000005373 I 0.914
MLXIPL Ochotona princeps ENSOPRG00000002458 I 0.914
MLXIPL Pteropus vampyrus ENSPVAG00000016410 I 0.914
ENSSTOG00000027367 Ictidomys tridecemlineatus ENSSTOG00000027367 I 0.914
Gfo_R013572 Geospiza fortis Gfo_R013572 I 0.914
Pvit_11967 Pogona vitticeps Pvit_11967 I 0.914
Alligator_sinensis_CCG018915.1 Alligator sinensis Alligator_sinensis_CCG018915.1 I 0.914
Afo_R005277 Aptenodytes forsteri Afo_R005277 I 0.914
MLXIPL Taeniopygia guttata ENSTGUG00000003070 I 0.914
Aan_R007283 Calypte anna Aan_R007283 I 0.914
MLXIPL Loxodonta africana ENSLAFG00000000706 I 0.914
MLXIPL Otolemur garnettii ENSOGAG00000015010 I 0.914
MLXIPL Canis familiaris ENSCAFG00000012970 I 0.914
Mlxipl Dipodomys ordii ENSDORG00000012167 I 0.914
MLXIPL Callithrix jacchus ENSCJAG00000016824 I 0.914
MLXIPL Cavia porcellus ENSCPOG00000010276 I 0.914
ENSFALG00000013690 Ficedula albicollis ENSFALG00000013690 I 0.914
MLXIPL Felis catus ENSFCAG00000004749 I 0.914
ENSAMEG00000011254 Ailuropoda melanoleuca ENSAMEG00000011254 I 0.914
ENSCSAG00000018176 Chlorocebus sabaeus ENSCSAG00000018176 I 0.914
MLXIPL Homo sapiens ENSG00000009950 D 0.914
MLXIPL Gorilla gorilla ENSGGOG00000016962 I 0.914
MLXIPL Equus caballus ENSECAG00000021590 I 0.901
ENSACAG00000007699 Anolis carolinensis ENSACAG00000007699 I 0.894
ENSSHAG00000015886 Sarcophilus harrisii ENSSHAG00000015886 I 0.888
ENSMPUG00000016074 Mustela putorius furo ENSMPUG00000016074 I 0.884
MLXIPL Echinops telfairi ENSETEG00000008859 I 0.871
MLXIPL Myotis lucifugus ENSMLUG00000005594 I 0.871
ENSAPLG00000007145 Anas platyrhynchos ENSAPLG00000007145 I 0.871
Myotis_brandtii_MLXIPL_10014270 Myotis brandtii Myotis_brandtii_MLXIPL_10014270 I 0.871
MLXIPL Dasypus novemcinctus ENSDNOG00000038567 I 0.867
MLXIPL Bos taurus ENSBTAG00000009153 I 0.858
MLXIPL Tursiops truncatus ENSTTRG00000016482 I 0.858
MLXIPL Sus scrofa ENSSSCG00000007710 I 0.858
ENSBTAP00000012060-D1 Bos grunniens ENSBTAP00000012060-D1 I 0.858
Ogr07070 Ophisaurus gracilis Ogr07070 I 0.855