ENSP00000320886 (Macaca fascicularis)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00010 (HLH) IPR001092 ENSP00000320886 T047229_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
MLXIPL
M02772_2.00 		Homo sapiens
DNCACGTGHH
DDCACGTGNH		 SELEX
Jolma et al.(2013)
MLXIPL_1 		0.914 1.000
MLXIPL
M09788_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CHREBP_Q6 		0.914 1.000
MLXIPL
M09789_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CHREB_Q6_01 		0.914 1.000
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000320886 bHLH 636 690

Links

Other bHLH family TFs
Other Macaca fascicularis TFs

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41 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action