ENSP00000331057 (Macaca fascicularis)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00010 (HLH) IPR001092 ENSP00000331057 T047234_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. This encoded protein is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Tcf12
M01740_2.00
Mus musculus
NVCAYCTGB

VCAGRTGBN
PBM
Weirauch et al.(2014)
pTH5071
0.914 1.000
TCF12
M04137_2.00
Homo sapiens
VCACSTGB

VCASGTGB
SELEX
Yin et al.(2017)
TCF12_eDBD_HT-SELEX
0.914 1.000
Tcf12
M08062_2.00
Mus musculus
RRCAGCTGNNN

NNNCAGCTGYY
ChIP-seq
Mathelier et al.(2014)
MA0521.1
0.914 1.000
TCF12
M07805_2.00
Homo sapiens
NVDSCAGSTGB

VCASCTGSHBN
ChIP-seq
Gerstein et al.(2012)
GM12878_TCF12_HudsonAlpha
0.914 1.000
TCF12
M07806_2.00
Homo sapiens
VCASCTGB

VCAGSTGB
ChIP-seq
Gerstein et al.(2012)
H1-hESC_TCF12_HudsonAlpha
0.914 1.000
TCF12
M08731_2.00
Homo sapiens
CMCASCTGSH

DSCAGSTGKG
Misc
Kulakovskiy et al.(2013)
HTF4_HUMAN.H11MO.0.A
0.914 1.000
Tcf12
M08762_2.00
Mus musculus
VMCASCTGSH

DSCAGSTGKB
Misc
Kulakovskiy et al.(2013)
HTF4_MOUSE.H11MO.0.A
0.914 1.000
TCF12
M09458_2.00
Homo sapiens
NNVCAGCTGB

VCAGCTGBNN
Misc
Heinz et al.(2010)
GM12878-Tcf12_GSE32465
0.914 1.000
TCF12
M09858_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$HEB_Q6
0.914 1.000
TCF12
M09859_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$HTF4_Q2
0.914 1.000
TCF12
M09860_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TCF12_01
0.914 1.000
TCF12
M09861_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TCF12_03
0.914 1.000
TCF12
M09862_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TCF12_05
0.914 1.000
TCF12
M04138_2.00
Homo sapiens
NCAYCTGN

NCAGRTGN
SELEX
Yin et al.(2017)
TCF12_eDBD_Methyl-HT-SELEX
0.914 1.000
Tcf3
M00753_2.00
Mus musculus
VCACCTGBN

NVCAGGTGB
PBM
Weirauch et al.(2013)
pTH3866
0.914 0.885
Tcf3
M01723_2.00
Mus musculus
NNVCACSTGB

VCASGTGBNN
PBM
Weirauch et al.(2014)
pTH4580
0.914 0.885
Tcf3
M00118_2.00
Mus musculus
VCAYCTGB

VCAGRTGB
PBM
Badis et al.(2009)
Tcfe2a_3865
0.914 0.885
Tcf4
M01750_2.00
Mus musculus
VCAGVTGBN

NVCABCTGB
PBM
Weirauch et al.(2014)
pTH5101
0.912 0.962
TCF4
M02807_2.00
Homo sapiens
HRCACCTGBN

NVCAGGTGYD
SELEX
Jolma et al.(2013)
TCF4_1
0.912 0.962
TCF4
M02808_2.00
Homo sapiens
NVCACCTBBN

NVVAGGTGBN
SELEX
Jolma et al.(2013)
TCF4_2
0.912 0.962
TCF4
M02728_2.00
Homo sapiens
RCACCTG

CAGGTGY
SELEX
Jolma et al.(2010)
TCF4_dimer
0.912 0.962
TCF4
M04214_2.00
Homo sapiens
VCACCTGB

VCAGGTGB
SELEX
Yin et al.(2017)
TCF4_eDBD_HT-SELEX
0.912 0.962
Tcf4
M08775_2.00
Mus musculus
HRCACCTGB

VCAGGTGYD
Misc
Kulakovskiy et al.(2013)
ITF2_MOUSE.H11MO.0.B
0.912 0.962
TCF4
M09461_2.00
Homo sapiens
ASWTCAAAGRVN

NBYCTTTGAWST
Misc
Heinz et al.(2010)
Hct116-Tcf4_SRA012054
0.912 0.962
TCF4
M04215_2.00
Homo sapiens
VCACCTGN

NCAGGTGB
SELEX
Yin et al.(2017)
TCF4_eDBD_Methyl-HT-SELEX
0.912 0.962
Tcf3
M09465_2.00
Mus musculus
ABWTCAAAGS

SCTTTGAWVT
Misc
Heinz et al.(2010)
mES-Tcf3_GSE11724
0.886 0.962
Tcf3
M09466_2.00
Mus musculus
VCAGCTGBNN

NNVCAGCTGB
Misc
Heinz et al.(2010)
proBcell-E2A_GSE21978
0.886 0.962
Tcf3
M09886_2.00
Mus musculus Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$E47_05
0.886 0.962
TCF3
M02775_2.00
Homo sapiens
NVCACCTGBN

NVCAGGTGBN
SELEX
Jolma et al.(2013)
TCF3_1
0.886 0.923
TCF3
M08710_2.00
Homo sapiens
VVCASCTGCHN

NDGCAGSTGBB
Misc
Kulakovskiy et al.(2013)
TFE2_HUMAN.H11MO.0.A
0.886 0.923
TCF3
M09791_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$E12_Q6
0.886 0.923
TCF3
M09792_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$E2A_Q6_01
0.886 0.923
TCF3
M09793_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$E2A_Q6_02
0.886 0.923
TCF3
M09794_2.00
Homo sapiens
VVVVMCACCTGCNBB

VVNGCAGGTGKBBBB
Transfac
Matys et al.(2006)
V$E47_01
0.886 0.923
TCF3
M09795_2.00
Homo sapiens
NNKWRCACCTGYDNNN

NNNHRCAGGTGYWMNN
Transfac
Matys et al.(2006)
V$E47_02
0.886 0.923
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000331057 bHLH 602 655

Links

Other bHLH family TFs
Other Macaca fascicularis TFs

212 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ARB_05189 Arthroderma benhamiae ARB_05189 N 0.000
AUEXF2481DRAFT_35837 Aureobasidium subglaciale AUEXF2481DRAFT_35837 N 0.000
BAUCODRAFT_118821 Baudoinia compniacensis BAUCODRAFT_118821 N 0.000
Bcin13g04470 Botrytis cinerea Bcin13g04470 N 0.000
BGHDH14_bgh02111 Blumeria graminis BGHDH14_bgh02111 N 0.000
CGGC5_11142 Colletotrichum gloeosporioides CGGC5_11142 N 0.000
DOTSEDRAFT_70172 Dothistroma septosporum DOTSEDRAFT_70172 N 0.000
estExt_fgenesh1_kg.C_chr_10255 Mycosphaerella graminicola estExt_fgenesh1_kg.C_chr_10255 N 0.000
EV44_g3378 Erysiphe necator EV44_g3378 N 0.000
GGTG_11436 Gaeumannomyces graminis GGTG_11436 N 0.000
GMDG_01897 Pseudogymnoascus destructans GMDG_01897 N 0.000
H101_07630 Trichophyton interdigitale H101_07630 N 0.000
H102_05371 Trichophyton rubrum H102_05371 N 0.000
H105_05414 Trichophyton soudanense H105_05414 N 0.000
M437DRAFT_58413 Aureobasidium melanogenum M437DRAFT_58413 N 0.000
M438DRAFT_351454 Aureobasidium pullulans M438DRAFT_351454 N 0.000
MCYG_04841 Arthroderma otae MCYG_04841 N 0.000
MCYG_04841 Microsporum canis MCYG_04841 N 0.000
MGG_01127 Magnaporthe oryzae MGG_01127 N 0.000
MGYG_08075 Microsporum gypseum MGYG_08075 N 0.000
MYCFIDRAFT_211282 Pseudocercospora fijiensis MYCFIDRAFT_211282 N 0.000
Mycgr3G102207 Zymoseptoria tritici Mycgr3G102207 N 0.000
PFICI_07310 Pestalotiopsis fici PFICI_07310 N 0.000
PV09_03847 Verruconis gallopava PV09_03847 N 0.000
SEPMUDRAFT_62999 Sphaerulina musiva SEPMUDRAFT_62999 N 0.000
SS1G_13549 Sclerotinia sclerotiorum SS1G_13549 N 0.000
TPHA_0H00790 Tetrapisispora phaffii TPHA_0H00790 I 0.000
TRV_03604 Trichophyton verrucosum TRV_03604 N 0.000
V499_08459 Pseudogymnoascus pannorum V499_08459 N 0.000
W97_02042 Coniosporium apollinis W97_02042 N 0.000